Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | AMD1 | P17707 | 1/20 | 0.39 |
| ▸ | AHCY | P23526 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14156814 | 0.91 | LMNA (0.48) | ADORA3ADORA2AADORA2BADORA1LMNA | |
| SCHEMBL25808148 | 0.81 | SLC29A1 (0.51) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL25808149 | 0.79 | HPGD (0.46) | TAS1R3TAS1R1 | |
| SCHEMBL14156805 | 0.78 | LMNA (0.57) | ADORA3ADORA2AADORA2BADORA1LMNA | |
| SCHEMBL14156811 | 0.78 | SLC29A1 (0.48) | ADORA3ADORA1LMNATP53CYP2C19 | |
| SCHEMBL25688810 | 0.75 | SLC29A1 (0.45) | LMNATP53 | |
| SCHEMBL22577618 | 0.72 | SLC29A1 (0.61) | ADORA3ADORA2AADORA2BADORA1TP53 | |
| SCHEMBL13777066 | 0.71 | DPP4 (0.59) | ADORA3ADORA2AADORA2BADORA1AMD1 | |
| SCHEMBL25496442 | 0.71 | DPP4 (0.59) | ADORA3ADORA2AADORA2BADORA1AMD1 | |
| SCHEMBL15962218 | 0.70 | PAX8 (0.49) | ADORA3ADORA2AADORA2BADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |