Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.46 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31685499 | 0.84 | LMNA (0.58) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL14156806 | 0.80 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL23710555 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL31685251 | 0.79 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL1120690 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL13296251 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL278167 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL13462039 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL25407962 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTTP53TDP1 | |
| SCHEMBL3422978 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |