Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.60 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.60 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.60 |
| ▸ | GAPDH | P04406 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | STAT6 | P42226 | 1/20 | 0.60 |
| ▸ | PI4KA | P42356 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thioguanosine SCHEMBL4527568 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL10017757 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL9791201 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL5557152 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL230739 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL230740 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL2619736 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL4527562 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL1981035 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL18249513 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |