Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.60 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.60 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.60 |
| ▸ | GAPDH | P04406 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | STAT6 | P42226 | 1/20 | 0.60 |
| ▸ | PI4KA | P42356 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thioguanosine SCHEMBL4527568 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL10017757 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL9791201 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL5557152 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL230739 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL2619736 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL4527562 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL1981035 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL14156817 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B | |
| Thioguanosine SCHEMBL18249513 | 1.00 | LMNA (0.62) | LMNANT5EHIF1AADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4577 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139030-A1 | CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION | SHATTUCK LABS INC (US) | 2026-05-21 | — | — | US | claimed |
| EP-4705481-A2 | CIRCULAR RNA COMPOSITIONS AND METHODS | Orna Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | claimed |
| US-20260049338-A1 | METHODS AND PRODUCTS FOR TRANSFECTING CELLS | FACTOR BIOSCIENCE INC (US) | 2026-02-19 | — | — | US | claimed |
| US-20250345406-A1 | CHIMERIC PROTEINS IN AUTOIMMUNITY | SHATTUCK LABS INC (US) | 2025-11-13 | — | — | US | claimed |
| US-20250325494-A1 | COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID | THEMEDIUM THERAPEUTICS CO., LTD. (CN) | 2025-10-23 | — | — | US | claimed |
| EP-4634380-A1 | INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION | ModernaTX, Inc. (US) | 2025-10-22 | — | — | EP | claimed |
| EP-4069255-B1 | IDENTIFYING NON-PRODUCTIVE SPLICE SITES | UNIV MASSACHUSETTS (US) | 2025-10-01 | — | — | EP | claimed |
| EP-3760734-B1 | NUCLEIC ACID MODIFICATION AND IDENTIFICATION METHOD | IMBA INST MOLEKULARE BIOTECH (AT) | 2025-08-20 | — | — | EP | claimed |
| US-12384740-B2 | Cationic lipids and transfection methods | FACTOR BIOSCIENCE INC. (US) | 2025-08-12 | — | — | US | claimed |
| US-20250241914-A1 | BIFUNCTIONAL PHARMACEUTICAL COMPOUNDS | DE MONTFORT UNIVERSITY (GB) | 2025-07-31 | — | — | US | claimed |
| WO-2002018404-A9 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | HOFFMANN LA ROCHE (CH) | 2003-10-02 | — | — | WO | claimed |
| EP-1315736-A2 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | claimed |
| US-20030008841-A1 | Anti-HCV nucleoside derivatives | F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) | 2003-01-09 | — | — | US | claimed |
| WO-2002018404-A2 | NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-07 | — | — | WO | claimed |
| US-5795752-A | GENETIC ENGINEERING | TRUSTEES OF DARTMOUTH COLLEGE (US) | 1998-08-18 | — | — | US | claimed |
| US-5734040-A | OLIGONUCLEOTIDES WITH ETHYLENEDIAMINE PHOSPHORAMIDATE FOR DNA | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1998-03-31 | — | — | US | claimed |
| WO-1993010230-A1 | LIGAND-STIMULATED GENE EXPRESSION | TRUSTEES OF DARTMOUTH COLLEGE (US) | 1993-05-27 | — | — | WO | claimed |
| WO-1989009778-A1 | OLIGONUCLEOTIDE CONTAINING 6-THIOGUANINE AT A PREDETERMINED SITE | CHEMICAL INDUSTRY INSTITUTE OF TOXICOLOGY (US) | 1989-10-19 | — | — | WO | claimed |
| EP-0038541-B1 | NOVEL PRODRUGS OF BIOLOGICALLY ACTIVE AGENTS CONTAINING MERCAPTO GROUPS, PROCESS FOR PREPARING AND THERAPEUTICALLY EFFECTIVE COMPOSITION CONTAINING THE SAME | MERCK & CO. INC. (US) | 1986-08-13 | — | — | EP | claimed |
| EP-0038541-A1 | Novel prodrugs of biologically active agents containing mercapto groups, process for preparing and therapeutically effective composition containing the same | MERCK & CO. INC. (US) | 1981-10-28 | — | — | EP | claimed |