Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939186 | 0.92 | LMNA (0.46) | LMNA | |
| SCHEMBL3430051 | 0.89 | LMNA (0.43) | LMNA | |
| SCHEMBL11723020 | 0.89 | LMNA (0.43) | LMNA | |
| SCHEMBL17825481 | 0.89 | LMNA (0.43) | LMNA | |
| SCHEMBL2972879 | 0.81 | — | — | |
| SCHEMBL11199752 | 0.81 | — | — | |
| SCHEMBL14656810 | 0.78 | LMNA (0.38) | LMNA | |
| SCHEMBL11312587 | 0.78 | TSHR (0.30) | — | |
| SCHEMBL28868791 | 0.75 | LMNA (0.45) | LMNAKDM1APTPN1MEN1CYP3A4 | |
| SCHEMBL3267922 | 0.74 | LMNA (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426398-A1 | BRANCHED-CHAIN AMINES IN ELECTROCHEMILUMINESCENCE DETECTION | Roche Diagnostics GmbH (DE) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017153574-A1 | BRANCHED-CHAIN AMINES IN ELECTROCHEMILUMINESCENCE DETECTION | ROCHE DIAGNOSTICS GMBH (DE) | 2017-09-14 | — | — | WO | disclosed |
| WO-2012170175-A1 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, OR AMELIORATING INFLAMMATORY PAIN | BAUSCH & LOMB INCORPORATED (US) | 2012-12-13 | — | — | WO | disclosed |