Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11723020 | 0.97 | LMNA (0.43) | LMNAHIF1AEPAS1 | |
| SCHEMBL17825481 | 0.97 | LMNA (0.43) | LMNAHIF1AEPAS1 | |
| SCHEMBL3430051 | 0.97 | LMNA (0.43) | LMNAHIF1AEPAS1 | |
| SCHEMBL14157367 | 0.92 | LMNA (0.41) | LMNA | |
| SCHEMBL11199752 | 0.85 | — | — | |
| SCHEMBL11312587 | 0.82 | TSHR (0.30) | — | |
| SCHEMBL2972879 | 0.79 | — | — | |
| SCHEMBL306390 | 0.79 | LMNA (0.42) | LMNAHIF1AEPAS1 | |
| SCHEMBL108076 | 0.74 | LMNA (0.71) | LMNAHIF1AEPAS1 | |
| SCHEMBL828040 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426398-A1 | BRANCHED-CHAIN AMINES IN ELECTROCHEMILUMINESCENCE DETECTION | Roche Diagnostics GmbH (DE) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017153574-A1 | BRANCHED-CHAIN AMINES IN ELECTROCHEMILUMINESCENCE DETECTION | ROCHE DIAGNOSTICS GMBH (DE) | 2017-09-14 | — | — | WO | disclosed |
| EP-0802255-B1 | Hydroxy-group containing acylated nitrogen compositions useful as additives for lubricating oil and fuel compositions | LUBRIZOL CORP (US) | 2001-12-12 | — | — | EP | disclosed |
| US-5696067-A | REACTING CERTAIN CARBOXYLIC REACTANTS WITH OLEFINIC COMPOUNDS THEN REACTING THE PRODUCT WITH AMMONIA, A HYDRAZINE OR AN AMINE | THE LUBRIZOL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0802255-A2 | Hydroxy-group containing acylated nitrogen compositions useful as additives for lubricating oil and fuel compositions | The Lubrizol Corporation (US) | 1997-10-22 | — | — | EP | disclosed |