Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19402607 | 0.87 | MAPK1 (0.47) | L3MBTL1LTA4HMEN1KMT2AMAPK1 | |
| SCHEMBL8773240 | 0.79 | L3MBTL1 (0.49) | L3MBTL1LMNALTA4HMEN1KMT2A | |
| SCHEMBL1671268 | 0.79 | L3MBTL1 (0.44) | L3MBTL1LMNAMAPTCYP1A2HTT | |
| SCHEMBL29506744 | 0.79 | L3MBTL1 (0.44) | L3MBTL1LMNAMAPTCYP1A2HTT | |
| SCHEMBL8773184 | 0.78 | MAOB (0.51) | LMNAHTTNUDT1NPSR1ALDH1A1 | |
| SCHEMBL31287990 | 0.78 | MAOB (0.51) | LMNAHTTNUDT1NPSR1ALDH1A1 | |
| SCHEMBL18951960 | 0.77 | MEN1 (0.50) | L3MBTL1LTA4HMEN1KMT2AMAPK1 | |
| SCHEMBL17413516 | 0.75 | LTA4H (0.55) | L3MBTL1LTA4HMEN1KMT2AMAPK1 | |
| SCHEMBL4268518 | 0.75 | LTA4H (0.60) | L3MBTL1LTA4HMEN1KMT2AMAPK1 | |
| SCHEMBL1415356 | 0.75 | L3MBTL1 (0.59) | L3MBTL1LMNAMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490360-B1 | THIAZOLIDINEDIONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARM CORP (KR) | 2011-03-16 | — | — | EP | disclosed |
| EP-1490360-A4 | THIAZOLIDINEDIONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARM CORP (KR) | 2006-07-05 | — | — | EP | disclosed |
| EP-1490360-A1 | THIAZOLIDINEDIONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003080605-A1 | THIAZOLIDINEDIONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2003-10-02 | — | — | WO | disclosed |