Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.57 |
| ▸ | CTSS | P25774 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14158080 | 0.92 | CTSK (0.57) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL14158039 | 0.92 | CTSK (0.52) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL14158030 | 0.91 | CTSK (0.57) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL14158041 | 0.89 | CTSK (0.55) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL14158040 | 0.87 | CTSK (0.52) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL14158005 | 0.87 | CTSK (0.52) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL14158085 | 0.86 | CTSK (0.52) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL14158078 | 0.86 | CTSK (0.52) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL14158047 | 0.85 | CTSK (0.51) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL14158000 | 0.85 | CTSL (0.54) | CTSKCTSSCTSLCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390804-B2 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-24 | — | — | US | disclosed |
| US-7390804-B2 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-24 | — | — | US | disclosed |