Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.49 |
| ▸ | CTSL | P07711 | 6/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14158214 | 0.92 | CTSK (0.41) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL14158033 | 0.90 | CTSK (0.54) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL14158091 | 0.88 | CTSK (0.50) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL14158092 | 0.86 | CTSK (0.53) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL14158281 | 0.86 | CTSL (0.52) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL14158035 | 0.86 | CTSK (0.48) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL14158063 | 0.85 | CTSK (0.49) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL14158244 | 0.85 | CTSK (0.49) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL14158064 | 0.84 | CTSK (0.49) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL14158058 | 0.84 | CTSK (0.53) | CTSKCTSLCTSBCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390804-B2 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-24 | — | — | US | disclosed |
| US-7390804-B2 | N-containing five-membered ring compounds and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-06-24 | — | — | US | disclosed |