SCHEMBL1415828

SCHEMBL1415828

COC(=O)C1=C(Nc2ccc(C)cc2)CC(C(=O)OC)=C(Nc2ccc(C)cc2)C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.48
▸ ALDH1A1 P00352 3/20 0.47
▸ MAPT P10636 3/20 0.47
▸ ACHE P22303 5/20 0.47
▸ SMN1; SMN2 Q16637 4/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ HPGD P15428 2/20 0.41
▸ TP53 P04637 2/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ CASP3 P42574 1/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12392802 0.94 ACHE (0.43) TDP1ALDH1A1MAPTACHESMN1; SMN2
SCHEMBL1415617 0.85 SLC6A3 (0.49) ALDH1A1MAPTACHENPC1RAB9A
SCHEMBL1415465 0.85 MEN1 (0.49) ALDH1A1MAPTACHESMN1; SMN2NPC1
SCHEMBL1415795 0.85 ACHE (0.44) TDP1ALDH1A1MAPTACHEHPGD
SCHEMBL1415808 0.85 HTT (0.54) TDP1ALDH1A1MAPTACHESMN1; SMN2
SCHEMBL3909905 0.84 MAPT (0.53) ALDH1A1MAPTACHESMN1; SMN2NPC1
SCHEMBL1415514 0.82 AKR1C3 (0.46) TDP1ALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL3905197 0.82 SLC6A3 (0.52) MAPTACHESMN1; SMN2NPC1RAB9A
SCHEMBL3902803 0.82 MAPT (0.45) TDP1ALDH1A1MAPTSMN1; SMN2NPC1
SCHEMBL3899783 0.81 EPHX2 (0.45) TDP1ALDH1A1ACHENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4582498-A1 PRINTING INK SET, PRINTED MATTER, AND PACKAGING MATERIAL Artience Co., Ltd. (JP) 2025-07-09 — — EP disclosed
WO-2024048522-A1 PRINTING INK SET, PRINTED MATTER, AND PACKAGING MATERIAL artience株式会社 2024-03-07 — — WO disclosed
WO-2023210260-A1 PRINTING INK SET, PRINTED MATTER, AND PACKAGING MATERIAL 東洋インキSCホールディングス株式会社 2023-11-02 — — WO disclosed
US-7947761-B2 Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups CABOT CORPORATION (US) 2011-05-24 — — US disclosed
EP-1399742-B1 QUINACRIDONE LABELLING REAGENTS FOR FLUORESCENCE DETECTION OF BIOLOGICAL MATERIALS GE HEALTHCARE UK LTD (GB) 2011-03-16 — — EP disclosed
EP-0632106-B2 Process for the production of 2,5-di(arylamino)-3,6- dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate TOYO INK MFG CO (JP) 2009-02-25 — — EP disclosed
US-20090017307-A1 Process for the Preparation of Organic Materials MCA TECHNOLOGIES, GMBH (CH) 2009-01-15 — — US disclosed
US-20090017307-A1 Process for the Preparation of Organic Materials MCA TECHNOLOGIES, GMBH (CH) 2009-01-15 — — US disclosed
US-20080060554-A1 Process for the Preparation of Organic Materials MCA TECHNOLOGIES, GMBH (CH) 2008-03-13 — — US disclosed
US-20080060554-A1 Process for the Preparation of Organic Materials MCA TECHNOLOGIES, GMBH (CH) 2008-03-13 — — US disclosed
US-5659036-A Process for the production of 2,5-di(arylamino)-3,6-dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate TOYO INK MANUFACTURING CO., LTD. (JP) 1997-08-19 — — US disclosed
US-5610306-A ALCOHOL ELIMINATION REACTION OF 2,5-DI(PHENYLAMINO)-3,6--DIHYDROTEREPHTHALIC ACID DIALKYL ESTER; CYCLIZATION TOYO INK MANUFACTURING CO., LTD. (JP) 1997-03-11 — — US disclosed
EP-0654472-A1 Process for the production of 6,13-dihydroquinacridones and apparatus for use for the production TOYO INK MANUFACTURING CO., LTD. (JP) 1995-05-24 — — EP disclosed
EP-0632106-A1 Process for the production of 2,5-di(arylamino)-3,6- dihydroterephthalic acid dialkyl ester, and process for the production of quinacridone from said ester as intermediate TOYO INK MANUFACTURING CO., LTD. (JP) 1995-01-04 — — EP disclosed
US-5367096-A Process for the preparation of 2,5-di(phenylamino)terephthalic acid and dialkyl esters thereof in high purity HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-22 — — US disclosed
US-5347038-A Starting material for quinacridone pigments, pollution control, from succinic acid diester and aniline HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-13 — — US disclosed
EP-0363756-B1 METHOD FOR THE PREPARATION OF 2,5-DIARYLAMINO-TEREPHTHALIC ACIDS BAYER AG (DE) 1992-12-02 — — EP disclosed
US-4981997-A Process for the preparation of 2,5-diarylaminoterephthalic acids BAYER AKTIENGESELLSCHAFT (DE) 1991-01-01 — — US disclosed
US-4758664-A Process for the preparation of linear quinacridones HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-19 — — US disclosed
EP-0204139-A2 Process for the manufacture of linear quinacridones HOECHST AKTIENGESELLSCHAFT (DE) 1986-12-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090017307-A1 Process for the Preparation of Organic Materials KLK4, PDK4, GRK1 TDP1 353/4885ALDH1A1 431/4885MAPT 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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