Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667517 | 0.75 | IDO1 (0.40) | KDM4EMAPTRIPK1PKMSMN1; SMN2 | |
| SCHEMBL861831 | 0.73 | RIPK1 (0.50) | MAPTRIPK1PKMSMN1; SMN2PSEN1 | |
| SCHEMBL14566097 | 0.73 | ALDH1A1 (0.42) | MAPTHTTTRPA1KMT2AMEN1 | |
| SCHEMBL24776611 | 0.72 | HSP90AA1 (0.36) | KDM4EMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL8202352 | 0.71 | MAPT (0.38) | KDM4EMAPTRIPK1PKMSMN1; SMN2 | |
| SCHEMBL8240380 | 0.71 | SLC6A4 (0.40) | KDM4EMAPTRIPK1PKMSMN1; SMN2 | |
| SCHEMBL16483392 | 0.71 | KDM4E (0.40) | KDM4EMAPTRIPK1PKMSMN1; SMN2 | |
| SCHEMBL14308115 | 0.70 | ALDH1A1 (0.44) | KDM4ESLC6A4HTT | |
| SCHEMBL1548511 | 0.70 | ALDH1A1 (0.50) | MAPTRIPK1PKMSMN1; SMN2HTR2A | |
| SCHEMBL5404811 | 0.70 | KCNH2 (0.56) | KDM4ERIPK1HTR2AKCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017183043-A1 | NOVEL PROCESS FOR THE PREPARATION OF TAVABOROLE, ITS NOVEL POLYMORPHIC FORMS AND THE POLYMORPHS THEREOF | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2017-10-26 | — | — | WO | disclosed |
| EP-1594878-B1 | AVERMECTIN MONOSACCHARIDE DERIVATIVES HAVING PESTICIDAL PROPERTIES | MERIAL LTD (GB) | 2008-06-04 | — | — | EP | disclosed |