Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 5/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | BRD1 | O95696 | 1/20 | 0.55 |
| ▸ | TAF1 | P21675 | 1/20 | 0.55 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693019 | 0.91 | ESR1 (0.58) | POLBAPAF1ESR1KMT2AALDH1A1 | |
| SCHEMBL10792923 | 0.89 | POLB (0.70) | POLBAPAF1ESR1ESR2KMT2A | |
| SCHEMBL14159191 | 0.83 | CA12 (0.73) | POLBAPAF1KMT2ACA12CA9 | |
| SCHEMBL14159134 | 0.82 | BRD4 (0.60) | POLBAPAF1ESR1ESR2KMT2A | |
| SCHEMBL7706718 | 0.81 | ERCC1 (0.70) | POLBKMT2AALDH1A1BRD1TAF1 | |
| SCHEMBL19404596 | 0.81 | BRD1 (0.79) | POLBKMT2AALDH1A1CA12CA9 | |
| SCHEMBL20735193 | 0.80 | ALDH1A1 (0.82) | POLBAPAF1KMT2AALDH1A1CA12 | |
| SCHEMBL10703784 | 0.80 | BRD1 (0.52) | POLBKMT2AALDH1A1BRD1TAF1 | |
| SCHEMBL8927321 | 0.80 | BRD1 (0.59) | POLBKMT2AALDH1A1BRD1TAF1 | |
| SCHEMBL14159133 | 0.78 | CA12 (0.52) | POLBAPAF1ESR1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930339-A2 | Imide compound | MITSUI CHEMICALS, INC. (JP) | 2008-06-11 | — | — | EP | disclosed |