SCHEMBL14159232

SCHEMBL14159232

Cc1c(-c2c(O)c(=O)c2=O)c(=O)n(-c2ccccc2)n1C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.67
ALDH1A1 P00352 1/20 0.67
BCHE P06276 1/20 0.54
PTGS2 P35354 1/20 0.54
LMNA P02545 4/20 0.53
ADORA3 P0DMS8 1/20 0.53
TSHR P16473 3/20 0.52
KMT2A Q03164 3/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CYP1A2 P05177 2/20 0.51
THRB P10828 1/20 0.51
NAPRT Q6XQN6 1/20 0.51
MAPT P10636 4/20 0.50
MEN1 O00255 1/20 0.50
CYP19A1 P11511 1/20 0.50
KDM4E B2RXH2 3/20 0.49
TP53 P04637 1/20 0.48
HSP90AA1 P07900 1/20 0.48
HSP90AB1 P08238 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL588715 0.87 ALDH1A1 (0.68) ALOX15ALDH1A1BCHEPTGS2LMNA
SCHEMBL151171 0.80 ALOX15 (1.00) ALOX15ALDH1A1BCHEPTGS2LMNA
SCHEMBL6889907 0.79 ALDH1A1 (0.62) ALOX15ALDH1A1BCHEPTGS2LMNA
SCHEMBL28668482 0.79 ALOX15 (0.62) ALOX15ALDH1A1BCHEPTGS2LMNA
SCHEMBL29086294 0.78 ALDH1A1 (0.61) ALOX15ALDH1A1BCHEPTGS2LMNA
SCHEMBL28914842 0.78 ALDH1A1 (0.60) ALOX15ALDH1A1BCHEPTGS2LMNA
SCHEMBL2449608 0.77 ALOX15 (0.68) ALOX15ALDH1A1BCHEPTGS2LMNA
SCHEMBL23673816 0.75 ALDH1A1 (0.57) ALOX15ALDH1A1BCHEPTGS2LMNA
Hydrochloric Acid SCHEMBL28311112 0.75 ALOX15 (0.66) ALOX15ALDH1A1BCHEPTGS2LMNA
SCHEMBL5190644 0.73 KMT2A (0.39) ALOX15ALDH1A1LMNAKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1930378-A1 Nitro schiff base metal complex dyes and their use with monosubstituted squaric acid dyes Clariant International Ltd. (CH) 2008-06-11 EP disclosed
EP-1925643-A1 Nitro schiff base metal complex dyes and their use in optical layers for optical data recording Clariant International Ltd. (CH) 2008-05-28 EP disclosed
US-20070196767-A1 Use Of Squaric Acid Dyes In Optical Layers For Optical Data Recording CLARIANT INTERNATIONAL LTD (CH) 2007-08-23 US disclosed
US-20070196767-A1 Use Of Squaric Acid Dyes In Optical Layers For Optical Data Recording CLARIANT INTERNATIONAL LTD (CH) 2007-08-23 US disclosed