Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335633 | 0.82 | APP (0.51) | MAPTCA1CA2APP | |
| SCHEMBL10227408 | 0.77 | TPMT (0.46) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL12954769 | 0.77 | TPMT (0.46) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL13364021 | 0.77 | TPMT (0.46) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL4083603 | 0.73 | TPMT (0.55) | TPMTCA1CA2GSK3BSLC22A2 | |
| SCHEMBL2954412 | 0.73 | TPMT (0.55) | TPMTCA1CA2GSK3BMEN1 | |
| SCHEMBL8257656 | 0.73 | TPMT (0.42) | TPMTCA1CA2GSK3BRXRA | |
| SCHEMBL824903 | 0.71 | MAPT (1.00) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL894135 | 0.71 | MEN1 (0.65) | MAPTHTTGFERHSD17B10GPR55 | |
| SCHEMBL10942166 | 0.71 | MAPT (1.00) | MAPTHTTGFERHSD17B10GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930308-A1 | Pharmaceutical agents for the treatment of cerebral amyloidosis | NYMOX CORPORATION (CA) | 2008-06-11 | — | — | EP | disclosed |