Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10204706 | 0.77 | MAPT (0.55) | CA1CA2 | |
| SCHEMBL10673423 | 0.75 | MAOA (0.57) | CA1CA2GSK3BMAOAMAOB | |
| SCHEMBL14632289 | 0.75 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL14072686 | 0.75 | PRSS1 (0.48) | CA1CA2MAOAMAOB | |
| SCHEMBL295411 | 0.75 | ALDH1A1 (0.44) | GSK3B | |
| SCHEMBL17868851 | 0.75 | TPMT (0.38) | TPMTCA1CA2GSK3BMAOA | |
| SCHEMBL93850 | 0.74 | MAOA (0.54) | MAOAMAOB | |
| SCHEMBL8569544 | 0.73 | TSHR (0.57) | TPMTCA1CA2 | |
| SCHEMBL14160201 | 0.73 | MAPT (0.55) | TPMTCA1CA2GSK3BRXRA | |
| SCHEMBL14072690 | 0.71 | CES2 (0.45) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |