SCHEMBL1416144

SCHEMBL1416144

[CH2]COC(=O)N(CCOCCO)CCOCCO

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
MAPK1 P28482 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416133 0.81 ALDH1A1 (0.42) TSHRBLMPMP22HSD17B10
SCHEMBL1416064 0.81 CA12 (0.32)
SCHEMBL10578182 0.77 TSHR (0.53) TSHRMAPK1MEN1KMT2A
SCHEMBL1416016 0.76 TSHR (0.42) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL23659151 0.76 MEN1 (0.41) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL1416287 0.76 TSHR (0.37) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL1416351 0.74 MEN1 (0.39) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL10619053 0.74 MEN1 (0.46) TSHRMAPK1MEN1KMT2A
SCHEMBL1415845 0.73 TSHR (0.39) TSHRMAPK1MEN1KMT2ABLM
SCHEMBL6318269 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2441783-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2015-03-04 EP disclosed
EP-2441783-A1 Polymerizable composition and lithographic printing plate precursor including the same, and lithographic printing method FUJIFILM Corporation (JP) 2012-04-18 EP disclosed
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2165830-A1 Lithographic printing plate precursor and printing method using the same Fujifilm Corporation (JP) 2010-03-24 EP disclosed