Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24092261 | 0.92 | MEN1 (0.37) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL14005175 | 0.82 | CHRNB2 (0.38) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL22098728 | 0.81 | MEN1 (0.42) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL13448559 | 0.76 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL10619053 | 0.76 | MEN1 (0.46) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL1416144 | 0.76 | TSHR (0.39) | MEN1KMT2ATSHRMAPK1HSD17B10 | |
| SCHEMBL14433146 | 0.75 | CHRNB2 (0.41) | TSHRCHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL22239380 | 0.75 | CA14 (0.41) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL2822780 | 0.73 | CHRNB2 (0.40) | TSHRMAPK1CHRNB2CHRNA4CHRM2 | |
| SCHEMBL14005100 | 0.72 | CA12 (0.41) | TSHRMAPK1ALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190951-A1 | CONJUGATES OF ANTIBODIES AN IMMUNE CELL ENGAGERS | SYNAFFIX B.V. (NL) | 2023-06-22 | — | — | US | disclosed |
| US-20230114866-A1 | VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES | SYNAFFIX B.V. (NL) | 2023-04-13 | — | — | US | disclosed |
| WO-2021144314-A1 | VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES | SYNAFFIX B.V. (NL) | 2021-07-22 | — | — | WO | disclosed |
| WO-2021144313-A1 | VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES | SYNAFFIX B.V. (NL) | 2021-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230114866-A1 | VIA CYCLOADDITION BILATERALLY FUNCTIONALIZED ANTIBODIES | FUT5, FUCA1, FUT6 | MEN1 568/4885KMT2A 2418/4885TSHR 1151/4885 |
| US-20230190951-A1 | CONJUGATES OF ANTIBODIES AN IMMUNE CELL ENGAGERS | FCGR3B, FCGR1A, FCGR2A | MEN1 2045/4885KMT2A 760/4885TSHR 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.