Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19760841 | 0.86 | KDM4E (0.54) | ALDH1A1KDM4EHPGDGLAATM | |
| SCHEMBL9243348 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDGLAATM | |
| SCHEMBL1321188 | 0.82 | MAOA (0.59) | ALDH1A1KDM4EHPGDGLANPC1 | |
| SCHEMBL29051268 | 0.80 | TSHR (0.57) | ALDH1A1KDM4EHPGDATMHSD17B10 | |
| SCHEMBL13742980 | 0.80 | CA12 (0.46) | ALDH1A1KDM4EHPGDATMKMT2A | |
| SCHEMBL1820406 | 0.78 | KDM4E (0.49) | ALDH1A1KDM4EHPGDGLAATM | |
| SCHEMBL20349961 | 0.77 | MAOA (0.54) | ALDH1A1KDM4EHPGDGLANPC1 | |
| SCHEMBL7067143 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDGLANQO1 | |
| SCHEMBL20346585 | 0.76 | ABCG2 (0.51) | ALDH1A1KDM4EHPGDGLAATM | |
| SCHEMBL20346631 | 0.75 | NPC1 (0.52) | ALDH1A1KDM4EHPGDATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113507-B2 | Process of preparation of aromatic polyols and rigid polyurethane and polyisocyanurate foams obtainable therefrom | ARCO CHEM TECH (US) | 1994-01-05 | — | — | EP | claimed |
| EP-0113507-B1 | Process of preparation of aromatic polyols and rigid polyurethane and polyisocyanurate foams obtainable therefrom | ARCO Chemical Technology, L.P. (US) | 1987-09-16 | — | — | EP | claimed |
| EP-0112627-B1 | AROMATIC AMIDO POLYOLS AND RIGID POLYURETHANE AND POLYISOCYANURATE FOAMS OBTAINABLE THEREFROM | TEXACO DEVELOPMENT CORPORATION (US) | 1986-09-17 | — | — | EP | claimed |
| EP-0113507-A1 | Process of preparation of aromatic polyols and rigid polyurethane and polyisocyanurate foams obtainable therefrom | ARCO Chemical Technology, L.P. (US) | 1984-07-18 | — | — | EP | claimed |
| EP-0112627-A1 | Aromatic amido polyols and rigid polyurethane and polyisocyanurate foams obtainable therefrom | TEXACO DEVELOPMENT CORPORATION (US) | 1984-07-04 | — | — | EP | claimed |
| US-4444918-A | Aromatic polyols made from waste streams from the manufacture of terephthalic acids, alkylene glycols and dibasic acids | TEXACO INC. (US) | 1984-04-24 | — | — | US | claimed |
| US-4442238-A | IMPROVED FIRE RESISTANCE | TEXACO INC. (US) | 1984-04-10 | — | — | US | claimed |
| EP-1058701-B2 | LOW VISCOSITY POLYESTER POLYOLS AND METHODS FOR PREPARING SAME | STEPAN CO (US) | 2011-03-16 | — | — | EP | disclosed |
| US-20100087560-A1 | POLYISOCYANURATE FOAM FOR ROOF STRUCTURES | DOW GLOBAL TECHNOLOGIES INC. | 2010-04-08 | — | — | US | disclosed |
| WO-2008144158-A1 | POLYISOCYANURATE FOAM FOR ROOF STRUCTURES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-11-27 | — | — | WO | disclosed |
| EP-1994070-A1 | SULFONATED AROMATIC POLYESTER POLYOL CMPOSITIONS | Oxid, L.P. (US) | 2008-11-26 | — | — | EP | disclosed |
| EP-0884339-B1 | Method for producing foams from high acid polyester polyols | DOW GLOBAL TECHNOLOGIES INC (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2007100489-A1 | SULFONATED AROMATIC POLYESTER POLYOL CMPOSITIONS | OXID, L.P. (US) | 2007-09-07 | — | — | WO | disclosed |
| EP-0112627-B1 | AROMATIC AMIDO POLYOLS AND RIGID POLYURETHANE AND POLYISOCYANURATE FOAMS OBTAINABLE THEREFROM | TEXACO DEVELOPMENT CORPORATION (US) | 1986-09-17 | — | — | EP | disclosed |
| EP-0113507-A1 | Process of preparation of aromatic polyols and rigid polyurethane and polyisocyanurate foams obtainable therefrom | ARCO Chemical Technology, L.P. (US) | 1984-07-18 | — | — | EP | disclosed |
| EP-0113172-A1 | Aromatic amino polyols and rigid polyurethane and polyisocyanurate foams obtainable therefrom | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1984-07-11 | — | — | EP | disclosed |
| EP-0112627-A1 | Aromatic amido polyols and rigid polyurethane and polyisocyanurate foams obtainable therefrom | TEXACO DEVELOPMENT CORPORATION (US) | 1984-07-04 | — | — | EP | disclosed |
| US-4444918-A | Aromatic polyols made from waste streams from the manufacture of terephthalic acids, alkylene glycols and dibasic acids | TEXACO INC. (US) | 1984-04-24 | — | — | US | disclosed |
| US-4442237-A | RIGID POLYURETHANE FOAMS | TEXACO INC. (US) | 1984-04-10 | — | — | US | disclosed |
| US-4442238-A | IMPROVED FIRE RESISTANCE | TEXACO INC. (US) | 1984-04-10 | — | — | US | disclosed |