SCHEMBL141627

SCHEMBL141627

COC(=O)c1ccc(C(=O)Oc2ccc(C(C)(C)c3ccc(OC)cc3)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.66
CA2 P00918 1/20 0.66
KMT2A Q03164 8/20 0.56
LMNA P02545 3/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MAPT P10636 6/20 0.54
TDP1 Q9NUW8 2/20 0.54
MEN1 O00255 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
KDM4E B2RXH2 1/20 0.54
ALDH1A1 P00352 2/20 0.53
ALOX15 P16050 1/20 0.53
APEX1 P27695 1/20 0.53
MAPK1 P28482 1/20 0.53
RECQL P46063 1/20 0.53
HSD17B10 Q99714 1/20 0.53
ACR P10323 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18016201 0.94 CA1 (0.75) CA1CA2KMT2ALMNASMN1; SMN2
SCHEMBL12451790 0.89 MAPT (0.69) CA1CA2KMT2ALMNACYP1A2
SCHEMBL12532604 0.89 TDP1 (0.61) CA1CA2KMT2AMAPTTDP1
SCHEMBL12345966 0.89 LMNA (0.54) CA1CA2KMT2ALMNACYP1A2
SCHEMBL25999958 0.89 LMNA (0.54) CA1CA2KMT2ALMNACYP1A2
SCHEMBL16775319 0.89 LMNA (0.54) CA1CA2KMT2ALMNACYP1A2
SCHEMBL13038154 0.88 CA1 (0.84) CA1CA2KMT2ALMNACYP1A2
SCHEMBL14226891 0.88 MAPT (0.52) CA1CA2KMT2ALMNACYP1A2
SCHEMBL141568 0.88 MAPT (0.71) KMT2ALMNACYP1A2CYP2C9CYP2C19
SCHEMBL14430927 0.85 KMT2A (0.50) CA1CA2KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 US disclosed
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 US disclosed