Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802303 | 0.80 | MEN1 (0.40) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL14579684 | 0.77 | CYP1A2 (0.57) | EGFRERBB2MEN1KMT2AHSD17B10 | |
| SCHEMBL12345948 | 0.76 | BRD4 (0.38) | MEN1KMT2AALDH1A1L3MBTL1PRSS1 | |
| SCHEMBL12346028 | 0.76 | SLC6A2 (0.44) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL141628 | 0.75 | CA1 (0.47) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL12345943 | 0.75 | KMT2A (0.47) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL12345950 | 0.72 | OPRM1 (0.38) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL21537921 | 0.71 | KMT2A (0.40) | EGFRERBB2MEN1KMT2AHSD17B10 | |
| SCHEMBL14579700 | 0.71 | KDM4E (0.44) | EGFRERBB2MEN1KMT2AHSD17B10 | |
| SCHEMBL18907050 | 0.70 | KMT2A (0.50) | EGFRERBB2MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189603-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF | FUJI ELECTRIC SYSTEMS CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |