Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520467 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAMAPTL3MBTL1 | |
| SCHEMBL20718866 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TDP1LMNAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11794578 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNAMAPTL3MBTL1 | |
| SCHEMBL2831747 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TDP1LMNAMAPTL3MBTL1 | |
| SCHEMBL10915469 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL20984139 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TDP1LMNAMAPTL3MBTL1 | |
| Bromide SCHEMBL20984477 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TDP1LMNAMAPTL3MBTL1 | |
| SCHEMBL8540751 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNAMAPTL3MBTL1 | |
| SCHEMBL3719830 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNAMAPTL3MBTL1 | |
| SCHEMBL8410359 | 0.79 | AR (0.64) | ALDH1A1MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718278-A1 | COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA-MEDIATED DISEASES | Philipps-Universität Marburg (DE) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012168345-A1 | COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA-MEDIATED DISEASES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012168345-A1 | COMPOUNDS AS PPAR BETA/DELTA INHIBITORS FOR TREATING PPAR BETA/DELTA-MEDIATED DISEASES | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2012-12-13 | — | — | WO | disclosed |