Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.56 |
| ▸ | RARB | P10826 | 6/20 | 0.55 |
| ▸ | RXRA | P19793 | 3/20 | 0.52 |
| ▸ | RXRB | P28702 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15814719 | 0.87 | DHODH (0.69) | DHODHRXRARXRB | |
| SCHEMBL16488615 | 0.87 | DHODH (0.69) | DHODHRXRARXRB | |
| SCHEMBL18604547 | 0.84 | DHODH (0.67) | DHODHRXRARXRB | |
| SCHEMBL4246903 | 0.84 | DHODH (0.67) | DHODHRXRARXRB | |
| Terephthalic Acid SCHEMBL28210383 | 0.83 | RARB (0.69) | RARBRXRARXRBMEN1ALDH1A1 | |
| SCHEMBL686581 | 0.82 | RXRA (0.65) | DHODHRXRARXRB | |
| SCHEMBL23346266 | 0.80 | EGFR (0.64) | DHODHRXRARXRB | |
| SCHEMBL23671728 | 0.80 | DHODH (0.81) | DHODHRXRARXRBMAPTDAO | |
| Water SCHEMBL28916522 | 0.80 | RXRA (0.63) | DHODHRXRARXRB | |
| SCHEMBL7607957 | 0.79 | RARB (0.65) | RARBMEN1ALDH1A1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012168151-A1 | COMPOSITIONS, METHODS AND USES | CASTROL LIMITED (GB) | 2012-12-13 | — | — | WO | disclosed |