SCHEMBL686581

SCHEMBL686581

O=C(O)c1ccc(-c2cc(C(=O)O)cc(C(=O)O)c2)cc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXRA P19793 6/20 0.65
RXRB P28702 5/20 0.65
DHODH Q02127 2/20 0.64
EGFR P00533 1/20 0.61
BCL2L1 Q07817 1/20 0.60
BAD Q92934 1/20 0.60
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
RXRG P48443 2/20 0.59
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
HSD17B10 Q99714 1/20 0.53
SRD5A2 P31213 1/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28916522 0.98 RXRA (0.63) RXRARXRBDHODHEGFRBCL2L1
SCHEMBL23346266 0.98 EGFR (0.64) RXRARXRBDHODHEGFRBCL2L1
SCHEMBL15120764 0.95 EGFR (0.67) RXRARXRBDHODHEGFRBCL2L1
SCHEMBL16488615 0.95 DHODH (0.69) RXRARXRBDHODHEGFRBCL2L1
SCHEMBL15814719 0.95 DHODH (0.69) RXRARXRBDHODHEGFRBCL2L1
Sulfur Dioxide SCHEMBL28919648 0.93 RXRA (0.59) RXRARXRBDHODHEGFRBCL2L1
SCHEMBL18604547 0.92 DHODH (0.67) RXRARXRBDHODHEGFRBCL2L1
SCHEMBL4246903 0.92 DHODH (0.67) RXRARXRBDHODHEGFRBCL2L1
SCHEMBL22734016 0.90 EGFR (0.72) RXRARXRBEGFRBCL2L1BAD
SCHEMBL21133337 0.90 EGFR (0.72) RXRARXRBEGFRBCL2L1BAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 887 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4285943-B1 SILICONE PATCH COMPRISING METAL-ORGANIC FRAMEWORK AND SILICONE COMPOSITION SEOUL NAT UNIV HOSPITAL (KR) 2026-03-18 EP claimed
CN-121571122-A MOF-based gas adsorption filter cloth and preparation method and application thereof 理工清科(重庆)先进材料研究院有限公司 2026-02-27 CN claimed
US-20250066641-A1 POLISHING SLURRY COMPOSITION AND METHOD OF MANUFACTURING INTEGRATED CIRCUIT DEVICE USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-02-27 US claimed
CN-119439618-A Negative photosensitive resin composition, preparation method thereof and hardening film 深圳市道尔顿电子材料股份有限公司 2025-02-14 CN claimed
CN-119101251-A Preparation method of medium Kong Lvji MOF material with excellent benzene diffusion capacity 浙江大学 2024-12-10 CN claimed
CN-118954449-A Total-hydrolysis amorphous-base trimetallic phosphide material and preparation method and application thereof 陕西科技大学 2024-11-15 CN claimed
US-20240269659-A1 FRUSTRATED LEWIS PAIR-IMPREGNATED POROUS MATERIALS AND USES THEREOF UNIVERSITY OF SOUTH FLORIDA 2024-08-15 US claimed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP claimed
US-20240216586-A1 SILICONE PATCH COMPRISING METAL-ORGANIC FRAMEWORK AND SILICONE COMPOSITION SOOKMYUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2024-07-04 US claimed
WO-2024019398-A1 METHOD FOR PREPARING METAL-ORGANIC FRAMEWORK WITH LOW AMOUNT OF IMPURITIES WITHOUT WASHING, AND METAL-ORGANIC FRAMEWORK 숙명여자대학교산학협력단 2024-01-25 WO claimed
US-20040127588-A1 Proton-conducting membrane and use thereof BASF FUEL CELL GMBH (DE) 2004-07-01 US claimed
WO-2004055097-A1 HIGH-MOLECULAR POLYAZOLES PEMEAS GMBH (DE) 2004-07-01 WO claimed
US-20040096734-A1 Proton-comducting membrane and the use thereof BASF FUEL CELL GMBH (DE) 2004-05-20 US claimed
WO-2004030135-A2 PROTON-CONDUCTING MEMBRANE AND USE THEREOF VERWENDUNG PEMEAS GMBH (DE) 2004-04-08 WO claimed
WO-2004024797-A1 POLYMER FILM BASED ON POLYAZOLES, AND USE THEREOF PEMEAS GMBH (DE) 2004-03-25 WO claimed
EP-1379572-A1 PROTON-CONDUCTING MEMBRANE AND THE USE THEREOF Celanese Ventures GmbH (DE) 2004-01-14 EP claimed
EP-1379573-A1 PROTON-CONDUCTING MEMBRANE AND USE THEREOF Celanese Ventures GmbH (DE) 2004-01-14 EP claimed
WO-2004003061-A1 PROTON-CONDUCTING MEMBRANE AND THE USE THEREOF PEMEAS GMBH (DE) 2004-01-08 WO claimed
WO-2002088219-A1 PROTON-CONDUCTING MEMBRANE AND USE THEREOF CELANESE VENTURES GMBH (DE) 2002-11-07 WO claimed
WO-2002081547-A1 PROTON-CONDUCTING MEMBRANE AND THE USE THEREOF CELANESE VENTURES GMBH (DE) 2002-10-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216586-A1 SILICONE PATCH COMPRISING METAL-ORGANIC FRAMEWORK AND SILICONE COMPOSITION CUTA, SMAD3, POF1B RXRA 2738/4885RXRB 2648/4885DHODH 4479/4885
US-20240269659-A1 FRUSTRATED LEWIS PAIR-IMPREGNATED POROUS MATERIALS AND USES THEREOF LPO, GPX4, NCF1 RXRA 2558/4885RXRB 3646/4885DHODH 4337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.