Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129823 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTATMDRD1SCN9A | |
| SCHEMBL9338866 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTATMDRD1KCNH2 | |
| SCHEMBL11187255 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTATMDRD1SCN9A | |
| SCHEMBL8237109 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTATMDRD1KCNH2 | |
| SCHEMBL7898118 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTATMDRD1SCN9A | |
| SCHEMBL15307367 | 0.73 | MAPT (0.55) | ALDH1A1MAPTATMDRD1KCNH2 | |
| SCHEMBL29716239 | 0.72 | KMT2A (0.40) | ALDH1A1DRD1 | |
| SCHEMBL22009635 | 0.72 | KMT2A (0.40) | ALDH1A1DRD1 | |
| SCHEMBL4318313 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPTATMDRD1SCN9A | |
| SCHEMBL2486479 | 0.72 | CSNK1A1 (0.54) | ALDH1A1MAPTATMKCNH2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426473-B2 | Phenoxy acetic acids as PPAR delta activators | High Point Pharnaceuticals, LLC (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120232080-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-09-13 | — | — | US | disclosed |
| US-8217086-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-07-10 | — | — | US | disclosed |
| EP-1899302-B1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20110183982-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-07-28 | — | — | US | disclosed |
| US-7943669-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-05-17 | — | — | US | disclosed |
| EP-2298742-A1 | Phenoxy acetic acids as PPAR delta activators | High Point Pharmaceuticals, LLC (US) | 2011-03-23 | — | — | EP | disclosed |
| US-20090192162-A1 | Phenoxy Acetic Acids as PPAR Delta Activators | TRANSTECH PHARMA, INC. (NC) | 2009-07-30 | — | — | US | disclosed |
| EP-1899302-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | Novo Nordisk A/S (DK) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003581-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192162-A1 | Phenoxy Acetic Acids as PPAR Delta Activators | PPARA, PPARG, PPARD | ALDH1A1 159/4885MAPT 2797/4885ATM 3569/4885 |
| US-20120232080-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARA, PPARG, PPARD | ALDH1A1 159/4885MAPT 2797/4885ATM 3569/4885 |
| US-20110183982-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARA, PPARG, PPARD | ALDH1A1 159/4885MAPT 2797/4885ATM 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.