Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11123455 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MAPTATMSCN9ADRD1 | |
| SCHEMBL8129823 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPTATMSCN9ADRD1 | |
| SCHEMBL7898118 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTATMSCN9ADRD1 | |
| SCHEMBL8237109 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTATMSCN9ADRD1 | |
| SCHEMBL9338866 | 0.84 | ALDH1A1 (0.59) | ALDH1A1MAPTATMSCN9ADRD1 | |
| SCHEMBL4318313 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPTATMSCN9ADRD1 | |
| SCHEMBL15307367 | 0.80 | MAPT (0.55) | ALDH1A1MAPTATMSCN9ADRD1 | |
| SCHEMBL2486479 | 0.79 | CSNK1A1 (0.54) | ALDH1A1MAPTATMSCN9ACSNK1A1 | |
| SCHEMBL11244530 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTATMSCN9ADRD1 | |
| SCHEMBL4318737 | 0.79 | LMNA (0.53) | ALDH1A1MAPTATMSCN9AFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414391-A | A process for preparing 2-pyridinyloxyphenoxy-lower-alkanoates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-11-08 | — | — | US | disclosed |
| EP-0040478-A1 | Process for preparing pyridine derivatives and intermediates useful in the process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-11-25 | — | — | EP | disclosed |
| EP-0030867-A1 | Process for the preparation of substituted pyridinyloxy ethers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |
| US-4266063-A | FROM A HALOPYRIDINE AND HYDROQUINONE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| EP-0003648-A2 | 4-Aryloxy-substituted phenoxypropionamide derivatives useful as herbicides, compositions containing them, and processes for making them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-08-22 | — | — | EP | disclosed |