Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18951697 | 0.86 | FFAR4 (0.40) | MAPTALDH1A1GAAHPGDPOLB | |
| SCHEMBL16953934 | 0.86 | MAPT (0.36) | MAPTSOD1ALDH1A1GAAHPGD | |
| SCHEMBL1417094 | 0.86 | MAPT (0.34) | MAPTSOD1ALDH1A1GAAHPGD | |
| Water SCHEMBL27733080 | 0.85 | MAPT (0.35) | MAPTSOD1ALDH1A1GAAHPGD | |
| Water SCHEMBL27733081 | 0.85 | MAPT (0.35) | MAPTSOD1ALDH1A1GAAHPGD | |
| SCHEMBL24156965 | 0.83 | MAPT (0.35) | MAPTALDH1A1GAAHPGDPOLB | |
| SCHEMBL16952753 | 0.83 | MAPT (0.36) | MAPTALDH1A1HPGDPOLBXBP1 | |
| SCHEMBL18304384 | 0.82 | MAOA (0.38) | MAPTSOD1ALDH1A1PLA2G7SMPD1 | |
| SCHEMBL16961433 | 0.82 | MAPT (0.34) | MAPTALDH1A1GAAHPGDPOLB | |
| SCHEMBL16956981 | 0.82 | MAPT (0.36) | MAPTALDH1A1GAAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021259208-A1 | TYK-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-12-30 | — | — | WO | disclosed |
| US-20200115339-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | Basilea Pharmaceutica International AG (CH) | 2020-04-16 | — | — | US | disclosed |
| US-10464896-B2 | Efflux-pump inhibitors and therapeutic uses thereof | Basilea Pharmaceutica International AG (CH) | 2019-11-05 | — | — | US | disclosed |
| US-20180179158-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | Basilea Pharmaceutica International AG (CH) | 2018-06-28 | — | — | US | disclosed |
| EP-3307725-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | Basilea Pharmaceutica International AG (CH) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016198691-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | BASILEA PHARMACEUTICA AG (CH) | 2016-12-15 | — | — | WO | disclosed |
| US-8426473-B2 | Phenoxy acetic acids as PPAR delta activators | High Point Pharnaceuticals, LLC (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120232080-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-09-13 | — | — | US | disclosed |
| US-8217086-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-07-10 | — | — | US | disclosed |
| EP-1899302-B1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20110183982-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-07-28 | — | — | US | disclosed |
| US-7943669-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-05-17 | — | — | US | disclosed |
| EP-2298742-A1 | Phenoxy acetic acids as PPAR delta activators | High Point Pharmaceuticals, LLC (US) | 2011-03-23 | — | — | EP | disclosed |
| US-20090192162-A1 | Phenoxy Acetic Acids as PPAR Delta Activators | TRANSTECH PHARMA, INC. (NC) | 2009-07-30 | — | — | US | disclosed |
| EP-1899302-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | Novo Nordisk A/S (DK) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003581-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192162-A1 | Phenoxy Acetic Acids as PPAR Delta Activators | PPARA, PPARG, PPARD | MAPT 2797/4885SOD1 3649/4885ALDH1A1 159/4885 |
| US-20200115339-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCC1, ABCC3 | MAPT 3746/4885SOD1 1061/4885ALDH1A1 347/4885 |
| US-20120232080-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARA, PPARG, PPARD | MAPT 2797/4885SOD1 3649/4885ALDH1A1 159/4885 |
| US-10464896-B2 | Efflux-pump inhibitors and therapeutic uses thereof | ABCB11, ABCC1, ABCC3 | MAPT 3744/4885SOD1 1126/4885ALDH1A1 349/4885 |
| US-20110183982-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARA, PPARG, PPARD | MAPT 2797/4885SOD1 3649/4885ALDH1A1 159/4885 |
| US-20180179158-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCC1, ABCC3 | MAPT 3744/4885SOD1 1126/4885ALDH1A1 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.