Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | CDC7 | O00311 | 4/20 | 0.53 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075311 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL11161509 | 0.87 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL28723241 | 0.87 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL11160196 | 0.87 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL330552 | 0.86 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL18342059 | 0.85 | ALDH1A1 (0.73) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL28816403 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL2691019 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL11284789 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HSD17B10CYP1A2MAPTMEN1 | |
| SCHEMBL16075306 | 0.83 | ALDH1A1 (0.81) | ALDH1A1HSD17B10CYP1A2MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057666-B | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 沈阳药科大学 | 2023-02-07 | — | — | CN | disclosed |
| CN-114057666-A | Synthesis method of 4, 5-disubstituted-2-aminothiazole compound | 沈阳药科大学 | 2022-02-18 | — | — | CN | disclosed |
| US-8975235-B2 | Lysophosphatidic acid receptor antagonists | INTERMUNE, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-8975235-B2 | Lysophosphatidic acid receptor antagonists | INTERMUNE, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-20130072449-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072449-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |
| EP-2480600-A1 | IRON(III)-COMPLEXING AGENT FOR STABILIZING COMB POLYMERS IN MINERAL BINDING AGENTS | Sika Technology AG (CH) | 2012-08-01 | — | — | EP | disclosed |
| US-20120178854-A1 | IRON(III)-COMPLEXING AGENTS FOR STABILIZING COMB POLYMERS IN MINERAL BINDING AGENTS | SIKA TECHNOLOGY AG (CH) | 2012-07-12 | — | — | US | disclosed |
| WO-2011033127-A1 | IRON(III)-COMPLEXING AGENT FOR STABILIZING COMB POLYMERS IN MINERAL BINDING AGENTS | SIKA TECHNOLOGY AG (CH) | 2011-03-24 | — | — | WO | disclosed |
| EP-2298833-A1 | Iron(III) complexing agents for stabilisation of comb polymers in mineral binding agents | Sika Technology AG (CH) | 2011-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178854-A1 | IRON(III)-COMPLEXING AGENTS FOR STABILIZING COMB POLYMERS IN MINERAL BINDING AGENTS | TAF5, TAF1, FECH | ALDH1A1 3995/4885HSD17B10 3798/4885CYP1A2 4489/4885 |
| US-20130072449-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | ALDH1A1 4135/4885HSD17B10 2376/4885CYP1A2 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.