Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.51 |
| ▸ | FNTB | P49356 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 3/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.47 |
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920142 | 0.86 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CYP1A2HPGDFNTA | |
| SCHEMBL6288104 | 0.86 | ALDH1A1 (0.69) | ALDH1A1HSD17B10CYP1A2HPGDFBP1 | |
| SCHEMBL1417293 | 0.84 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2HPGDFBP1 | |
| SCHEMBL11161509 | 0.84 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2HPGDFBP1 | |
| SCHEMBL28723241 | 0.84 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2HPGDFBP1 | |
| SCHEMBL11160196 | 0.84 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2HPGDFBP1 | |
| SCHEMBL330552 | 0.83 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP1A2HPGDFBP1 | |
| SCHEMBL28816403 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HSD17B10CYP1A2HPGDFBP1 | |
| SCHEMBL1777440 | 0.80 | HRH2 (0.47) | ALDH1A1HSD17B10CYP1A2HPGDFNTA | |
| SCHEMBL16075306 | 0.80 | ALDH1A1 (0.81) | ALDH1A1HSD17B10CYP1A2HPGDFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | ALDH1A1 2042/4885HSD17B10 1793/4885CYP1A2 1304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.