SCHEMBL14173333

SCHEMBL14173333

C=C(C)C(=O)OCC(O)COc1ccc(Oc2ccc(Oc3ccc(OCC(O)COC(=O)C(=C)C)cc3)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.55
MAPT P10636 3/20 0.55
LMNA P02545 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.50
CYP1A2 P05177 2/20 0.49
TSHR P16473 2/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ACACB O00763 1/20 0.43
ACACA Q13085 1/20 0.43
PLA2G4B P0C869 1/20 0.42
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
OPRK1 P41145 1/20 0.41
MEN1 O00255 1/20 0.41
CYP2D6 P10635 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14173320 1.00 POLB (0.55) POLBMAPTLMNANPSR1SMN1; SMN2
SCHEMBL11052821 0.94 POLB (0.50) POLBMAPTLMNANPSR1SMN1; SMN2
SCHEMBL15713256 0.91 POLB (0.55) POLBMAPTLMNANPSR1SMN1; SMN2
SCHEMBL17319414 0.90 POLB (0.54) POLBMAPTLMNANPSR1SMN1; SMN2
SCHEMBL28544663 0.90 POLB (0.54) POLBMAPTLMNANPSR1SMN1; SMN2
SCHEMBL18058329 0.90 POLB (0.54) POLBMAPTLMNANPSR1SMN1; SMN2
SCHEMBL2032040 0.90 POLB (0.54) POLBMAPTLMNANPSR1SMN1; SMN2
SCHEMBL23573047 0.88 POLB (0.53) POLBMAPTLMNANPSR1SMN1; SMN2
SCHEMBL3194809 0.88 POLB (0.53) POLBMAPTLMNANPSR1SMN1; SMN2
SCHEMBL13144353 0.88 POLB (0.53) POLBMAPTLMNANPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-20080138725-A1 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY LIMITED (JP) 2008-06-12 US disclosed
US-20080138725-A1 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY LIMITED (JP) 2008-06-12 US disclosed