Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14173320 | 0.90 | POLB (0.55) | POLBMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL15713256 | 0.90 | POLB (0.55) | POLBMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL14173333 | 0.90 | POLB (0.55) | POLBMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL17319414 | 0.88 | POLB (0.54) | POLBMAPTLMNANPSR1SMN1; SMN2 | |
| SCHEMBL18058329 | 0.88 | POLB (0.54) | POLBMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL2032040 | 0.88 | POLB (0.54) | POLBMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL23573047 | 0.87 | POLB (0.53) | POLBMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL819038 | 0.87 | POLB (0.53) | POLBMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL11649744 | 0.87 | CYP1A2 (0.65) | POLBMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL12576375 | 0.87 | POLB (0.60) | POLBMAPTLMNANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112930487-A | Ophthalmic device | 鲍希与洛姆伯股份有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-112601987-A | High water content ophthalmic devices | 鲍希与洛姆伯股份有限公司 | 2021-04-02 | — | — | CN | claimed |
| CN-112930487-A | Ophthalmic device | 鲍希与洛姆伯股份有限公司 | 2021-06-08 | — | — | CN | disclosed |