Sugi Predict

Sugi Predict / Compounds / SCHEMBL2032040

SCHEMBL2032040

SCHEMBL2032040

C=C(C)C(=O)OCC(O)COc1ccc(C)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.54
▸ LMNA P02545 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ NPSR1 Q6W5P4 2/20 0.54
▸ TSHR P16473 2/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ USP2 O75604 1/20 0.49
▸ CYP1A2 P05177 3/20 0.48
▸ CYP3A4 P08684 2/20 0.45
▸ CYP2C9 P11712 2/20 0.45
▸ CYP2C19 P33261 2/20 0.45
▸ ATM Q13315 1/20 0.45
▸ APEX1 P27695 1/20 0.45
▸ HTT P42858 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ CYP2D6 P10635 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14173320 0.90 POLB (0.55) POLBLMNAMAPTNPSR1TSHR
SCHEMBL15713256 0.90 POLB (0.55) POLBLMNAMAPTNPSR1TSHR
SCHEMBL14173333 0.90 POLB (0.55) POLBLMNAMAPTNPSR1TSHR
SCHEMBL17319414 0.88 POLB (0.54) POLBLMNAMAPTNPSR1TSHR
SCHEMBL18058329 0.88 POLB (0.54) POLBLMNAMAPTNPSR1TSHR
SCHEMBL28544663 0.88 POLB (0.54) POLBLMNAMAPTNPSR1TSHR
SCHEMBL23573047 0.87 POLB (0.53) POLBLMNAMAPTNPSR1TSHR
SCHEMBL12576375 0.87 POLB (0.60) POLBLMNAMAPTNPSR1SMN1; SMN2
SCHEMBL11649744 0.87 CYP1A2 (0.65) POLBLMNAMAPTNPSR1TSHR
SCHEMBL819038 0.87 POLB (0.53) POLBLMNAMAPTNPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3004050-B1 CYANOSTILBENES ROLIC TECH AG (CH) 2020-09-02 — — EP disclosed
CN-111533668-A Cyanostilbenes 罗利克技术有限公司 2020-08-14 — — CN disclosed
US-10329486-B2 Cyanostilbenes ROLIC AG (CH) 2019-06-25 — — US disclosed
US-9511004-B2 Dental material, dental material composition, dental restorative material, and cured product MITSUI CHEMICALS, INC. (JP) 2016-12-06 — — US disclosed
US-9504632-B2 Compound, composition comprising the compound and cured product MITSUI CHEMICALS, INC. (JP) 2016-11-29 — — US disclosed
EP-3004050-A1 CYANOSTILBENES Rolic AG (CH) 2016-04-13 — — EP disclosed
US-20160083655-A1 CYANOSTILBENES ROLIC AG (CH) 2016-03-24 — — US disclosed
CN-105377811-A Cyanostilbenes ROLIC AG 2016-03-02 — — CN disclosed
US-8906981-B2 Dental compositions comprising semi-crystalline resin and nanocluster filler 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-12-09 — — US disclosed
US-8906981-B2 Dental compositions comprising semi-crystalline resin and nanocluster filler 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-12-09 — — US disclosed
US-20120296003-A1 DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL RESTORATIVE MATERIAL, AND CURED PRODUCT MITSUI CHEMICALS, INC (JP) 2012-11-22 — — US disclosed
US-20120296061-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE COMPOUND AND CURED PRODUCT MITSUI CHEMICALS, INC. (JP) 2012-11-22 — — US disclosed
US-7959990-B2 Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light ROLIC AG (CH) 2011-06-14 — — US disclosed
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS SEPTODONT CONFI-DENTAL DIVISION (US) 2010-12-09 — — US disclosed
US-20080318188-A1 Dimer Acid-Derived Dimethacrylates and Use in Dental Restorative Compositions THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2008-12-25 — — US disclosed
US-20080274304-A1 Functionalized Photoreactive Compounds ROLIC AG (CH) 2008-11-06 — — US disclosed
EP-1928979-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS Rolic AG (CH) 2008-06-11 — — EP disclosed
WO-2007033506-A1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2007-03-29 — — WO disclosed
EP-1764405-A1 Functionalized photoreactive compounds Rolic AG (CH) 2007-03-21 — — EP disclosed
US-4416975-A Photopolymerization process employing compounds containing acryloyl groups and maleimide groups CIBA-GEIGY CORPORATION (US) 1983-11-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274304-A1 Functionalized Photoreactive Compounds PCNA, PIN1, MAP1LC3C POLB 610/4885LMNA 1132/4885MAPT 1166/4885
US-20100307378-A1 CARBAMATE-METHACRYLATE MONOMERS AND THEIR USE IN DENTAL APPLICATIONS CAD, ACMSD, MMAB POLB 2038/4885LMNA 1883/4885MAPT 775/4885
US-20080318188-A1 Dimer Acid-Derived Dimethacrylates and Use in Dental Restorative Compositions GRM7, NR2C2, GRM8 POLB 2428/4885LMNA 4355/4885MAPT 3085/4885
US-20160083655-A1 CYANOSTILBENES LATS1, LATS2, CRY1 POLB 1420/4885LMNA 166/4885MAPT 930/4885
US-20120296061-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE COMPOUND AND CURED PRODUCT GGPS1, FDFT1, FDPS POLB 1647/4885LMNA 3306/4885MAPT 574/4885
US-10329486-B2 Cyanostilbenes LATS1, LATS2, CRY1 POLB 1420/4885LMNA 166/4885MAPT 930/4885
US-20120296003-A1 DENTAL MATERIAL, DENTAL MATERIAL COMPOSITION, DENTAL RESTORATIVE MATERIAL, AND CURED PRODUCT CAD, SEM1, REV1 POLB 592/4885LMNA 2152/4885MAPT 532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.