SCHEMBL14174166

SCHEMBL14174166

CC1(C)c2cc(N)ccc2-c2ccc3c(c21)C(C)(C)c1cc(Br)ccc1-3

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
PDK2 Q15119 2/20 0.35
HTR2B P41595 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
IDO1 P14902 1/20 0.32
GPR35 Q9HC97 1/20 0.32
CHEK1 O14757 1/20 0.31
PRKD3 O94806 1/20 0.31
MAP4K4 O95819 1/20 0.31
RET P07949 1/20 0.31
MET P08581 1/20 0.31
PDGFRA P16234 1/20 0.31
FLT1 P17948 1/20 0.31
LTK P29376 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14305890 0.91 MAPT (0.45) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL31408561 0.91 MAPT (0.45) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL14174130 0.89 MAPT (0.44) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL10227282 0.89 PDK2 (0.41) ALDH1A1MAPK1PDK2HTR2BSIGMAR1
SCHEMBL12820530 0.85 ALDH1A1 (0.40) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL14174167 0.81 PDK2 (0.50) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL14174170 0.81 SMN1; SMN2 (0.38) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL14174168 0.79 PDK2 (0.38) ALDH1A1PDK2AKR1A1AKR1B1BACE1
SCHEMBL5063493 0.79 PDK2 (0.42) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL5013191 0.79 PDK2 (0.42) MAPTALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8334058-B2 Emitters for systems which emit in dark blue; stable, significantly longer lifetime; can be sublimed well without decomposition; easier to process; more suitable for OLEDs; operating voltage, power efficiency remain unchanged at large layer thicknesses; important for production of full-colour displays MERCK PATENT GMBH (DE) 2012-12-18 US disclosed
US-20080145708-A1 Compounds For Organic Electronic Devices MERCK PATENT GMBH (DE) 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145708-A1 Compounds For Organic Electronic Devices TYR, TOE1, GPX1 MAPT 589/4885ALDH1A1 58/4885KDM4E 1824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.