SCHEMBL14174180

SCHEMBL14174180

Nc1ccc2c(c1)oc1c2ccc2c3ccccc3oc21

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.79
ALDH1A1 P00352 6/20 0.79
MEN1 O00255 5/20 0.79
MAPT P10636 5/20 0.79
KDM4E B2RXH2 5/20 0.79
HPGD P15428 5/20 0.79
RAB9A P51151 6/20 0.63
NPC1 O15118 4/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
AHR P35869 3/20 0.48
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
DYRK1A Q13627 1/20 0.45
ADRB2 P07550 1/20 0.44
NQO1 P15559 1/20 0.44
GAA P10253 3/20 0.43
CASP1 P29466 2/20 0.43
CASP7 P55210 2/20 0.43
HSD17B10 Q99714 2/20 0.43
CA12 O43570 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483639 0.90 MAPT (0.96) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL31261599 0.90 MAPT (0.96) KMT2AALDH1A1MEN1MAPTKDM4E
Hydrochloric Acid SCHEMBL11439943 0.88 MAPT (1.00) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL14174147 0.86 MAPT (0.89) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL19988001 0.84 ALDH1A1 (0.61) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL1635471 0.83 AHR (0.52) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL30975195 0.83 ALDH1A1 (0.59) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL27838764 0.83 ALDH1A1 (0.59) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL22301470 0.81 ALDH1A1 (0.79) KMT2AALDH1A1MEN1MAPTKDM4E
SCHEMBL22137185 0.80 ALDH1A1 (0.56) KMT2AALDH1A1MEN1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8334058-B2 Emitters for systems which emit in dark blue; stable, significantly longer lifetime; can be sublimed well without decomposition; easier to process; more suitable for OLEDs; operating voltage, power efficiency remain unchanged at large layer thicknesses; important for production of full-colour displays MERCK PATENT GMBH (DE) 2012-12-18 US disclosed
US-20080145708-A1 Compounds For Organic Electronic Devices MERCK PATENT GMBH (DE) 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145708-A1 Compounds For Organic Electronic Devices TYR, TOE1, GPX1 KMT2A 1816/4885ALDH1A1 58/4885MEN1 997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.