SCHEMBL14174147

SCHEMBL14174147

Nc1ccc2c(c1)oc1cc3c(cc12)oc1ccccc13

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.89
KMT2A Q03164 5/20 0.89
ALDH1A1 P00352 5/20 0.89
HPGD P15428 5/20 0.89
MEN1 O00255 4/20 0.89
KDM4E B2RXH2 4/20 0.89
RAB9A P51151 6/20 0.78
SMN1; SMN2 Q16637 5/20 0.78
NPC1 O15118 4/20 0.78
AHR P35869 2/20 0.55
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.51
ADRB2 P07550 1/20 0.49
GFER P55789 1/20 0.47
NQO1 P15559 1/20 0.46
MAOA P21397 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
GLA P06280 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483639 0.96 MAPT (0.96) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL31261599 0.96 MAPT (0.96) MAPTKMT2AALDH1A1HPGDMEN1
Hydrochloric Acid SCHEMBL11439943 0.94 MAPT (1.00) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL20209307 0.89 KDM4E (0.69) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL257005 0.88 MAPT (1.00) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL22301470 0.86 ALDH1A1 (0.79) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL14174180 0.86 KMT2A (0.79) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL136810 0.85 KMT2A (0.73) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL16919496 0.85 AHR (0.71) MAPTKMT2AALDH1A1HPGDMEN1
SCHEMBL1547415 0.85 KDM4E (0.75) MAPTKMT2AALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423455-B1 SEMICONDUCTING POLYMER CLAP CO LTD (KR) 2021-06-23 EP disclosed
EP-3551635-B1 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2021-04-28 EP disclosed
EP-3166949-B1 THIENOTHIOPHENE-ISOINDIGO CLAP CO LTD (KR) 2021-02-17 EP disclosed
EP-3464415-B1 SEMICONDUCTORS BASF SE (DE) 2020-08-19 EP disclosed
EP-3386989-B1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2019-10-23 EP disclosed
WO-2018104367-A2 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2018-06-14 WO disclosed
WO-2017202635-A1 SEMICONDUCTORS BASF SE (DE) 2017-11-30 WO disclosed
WO-2017097924-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2017-06-15 WO disclosed
WO-2017089952-A1 DEGRADABLE CONJUGATED POLYMERS The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel (US) 2017-06-01 WO disclosed
US-8334058-B2 Emitters for systems which emit in dark blue; stable, significantly longer lifetime; can be sublimed well without decomposition; easier to process; more suitable for OLEDs; operating voltage, power efficiency remain unchanged at large layer thicknesses; important for production of full-colour displays MERCK PATENT GMBH (DE) 2012-12-18 US disclosed
US-20080145708-A1 Compounds For Organic Electronic Devices MERCK PATENT GMBH (DE) 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145708-A1 Compounds For Organic Electronic Devices TYR, TOE1, GPX1 MAPT 589/4885KMT2A 1816/4885ALDH1A1 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.