Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155473 | 0.90 | CA12 (0.38) | CA12CA1CA9PREPCYP4F2 | |
| SCHEMBL5921536 | 0.90 | CA12 (0.38) | CA12CA1CA9PREPCYP4F2 | |
| SCHEMBL17974012 | 0.85 | CA12 (0.36) | CA12CA1CA9PREPIDO1 | |
| SCHEMBL4404635 | 0.85 | CA12 (0.36) | CA12CA1CA9PREPIDO1 | |
| SCHEMBL23723314 | 0.82 | CA12 (0.42) | CA12CA1CA9PREP | |
| SCHEMBL1416957 | 0.82 | CA12 (0.42) | CA12CA1CA9PREPIDO1 | |
| SCHEMBL4694107 | 0.79 | IDO1 (0.38) | IDO1 | |
| SCHEMBL5855438 | 0.78 | PTGS2 (0.44) | CA1CA9 | |
| SCHEMBL29851528 | 0.77 | KDR (0.41) | CA12CA1CA9IDO1 | |
| SCHEMBL559965 | 0.77 | KDR (0.41) | CA12CA1CA9IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145247-A1 | Aminomethyl-Biaryl Derivatives Complement Factor D inhibitors and uses thereof | NOVARTIS AG (CH) | 2016-05-26 | — | — | US | disclosed |
| EP-3022182-A1 | AMINOMETHYL-BIARYL DERIVATIVES AS COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF | Novartis AG (CH) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015009977-A1 | AMINOMETHYL-BIARYL DERIVATIVES AS COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2015-01-22 | — | — | WO | disclosed |
| US-8426473-B2 | Phenoxy acetic acids as PPAR delta activators | High Point Pharnaceuticals, LLC (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426473-B2 | Phenoxy acetic acids as PPAR delta activators | High Point Pharnaceuticals, LLC (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426473-B2 | Phenoxy acetic acids as PPAR delta activators | High Point Pharnaceuticals, LLC (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120232080-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-09-13 | — | — | US | disclosed |
| US-20120232080-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-09-13 | — | — | US | disclosed |
| US-8217086-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-07-10 | — | — | US | disclosed |
| US-8217086-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-07-10 | — | — | US | disclosed |
| EP-1899302-B1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20110183982-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-07-28 | — | — | US | disclosed |
| US-20110183982-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-07-28 | — | — | US | disclosed |
| US-7943669-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-05-17 | — | — | US | disclosed |
| US-7943669-B2 | Phenoxy acetic acids as PPAR delta activators | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-05-17 | — | — | US | disclosed |
| EP-2298742-A1 | Phenoxy acetic acids as PPAR delta activators | High Point Pharmaceuticals, LLC (US) | 2011-03-23 | — | — | EP | disclosed |
| US-20090192162-A1 | Phenoxy Acetic Acids as PPAR Delta Activators | TRANSTECH PHARMA, INC. (NC) | 2009-07-30 | — | — | US | disclosed |
| US-20090192162-A1 | Phenoxy Acetic Acids as PPAR Delta Activators | TRANSTECH PHARMA, INC. (NC) | 2009-07-30 | — | — | US | disclosed |
| EP-1899302-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | Novo Nordisk A/S (DK) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003581-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192162-A1 | Phenoxy Acetic Acids as PPAR Delta Activators | PPARA, PPARG, PPARD | CA12 4294/4885CA1 3566/4885CA9 2721/4885 |
| US-20120232080-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARA, PPARG, PPARD | CA12 4294/4885CA1 3566/4885CA9 2721/4885 |
| US-20160145247-A1 | Aminomethyl-Biaryl Derivatives Complement Factor D inhibitors and uses thereof | CFD, CFH, CFB | CA12 4564/4885CA1 4815/4885CA9 2940/4885 |
| US-20110183982-A1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | PPARA, PPARG, PPARD | CA12 4294/4885CA1 3566/4885CA9 2721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.