SCHEMBL1417499

SCHEMBL1417499

[CH2]C(CNC(=O)CC#N)NC(=O)CC#N

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 5/20 0.48
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP3A4 P08684 1/20 0.35
HSD17B10 Q99714 1/20 0.33
KMT2A Q03164 1/20 0.33
ACACB O00763 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9442189 0.75 MCL1 (0.56) MCL1ALDH1A1KDM4ECYP3A4HSD17B10
SCHEMBL615361 0.74 MCL1 (0.59) MCL1ALDH1A1KDM4ECYP3A4HSD17B10
SCHEMBL8077349 0.72 MCL1 (0.52) MCL1ALDH1A1KDM4ECYP3A4HSD17B10
SCHEMBL10428283 0.72 MCL1 (0.57) MCL1ALDH1A1KDM4ECYP3A4HSD17B10
SCHEMBL8072203 0.71 MCL1 (0.50) MCL1ALDH1A1KDM4ECYP3A4HSD17B10
SCHEMBL1417434 0.70
SCHEMBL1418000 0.70 MCL1 (0.38) MCL1
SCHEMBL6217575 0.69 MCL1 (0.74) MCL1ALDH1A1KDM4ECYP3A4HSD17B10
SCHEMBL24988613 0.69 MCL1 (0.48) MCL1ALDH1A1KDM4ECYP3A4HSD17B10
SCHEMBL1896933 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1798258-B1 Polymer composition ROHM & HAAS (US) 2011-03-16 EP claimed
EP-1798258-A1 Polymer composition Rohm and Haas Company (US) 2007-06-20 EP claimed
EP-2235102-B1 METHOD FOR MANUFACTURING SCRUB AND STAIN-RESISTANT COATING COMPOSITIONS MASCO CORP (US) 2021-03-24 EP disclosed
EP-2077301-B1 Scrub and stain-resistant coating ROHM & HAAS (US) 2016-10-19 EP disclosed
EP-2518109-B1 Stabilised aqueous compositions comprising cationic polymers that deliver paint and primer properties in a coating ROHM & HAAS (US) 2015-06-17 EP disclosed
EP-2518109-A1 Stabilised aqueous compositions comprising cationic polymers that deliver paint and primer properties in a coating Rohm and Haas Company (US) 2012-10-31 EP disclosed
EP-1798258-B1 Polymer composition ROHM & HAAS (US) 2011-03-16 EP disclosed
EP-2235102-A1 SCRUB AND STAIN-RESISTANT COATING COMPOSITIONS, METHOD FOR MANUFACTURING THEREOF AND ARTICLES COMPRISING THE SAME Masco Corporation (US) 2010-10-06 EP disclosed
EP-1845142-B1 Dirt pickup resistant coating binder having high adhesion to substrates ROHM & HAAS (US) 2010-05-26 EP disclosed
WO-2009088792-A1 SCRUB AND STAIN-RESISTANT COATING COMPOSITIONS, METHOD FOR MANUFACTURING THEREOF AND ARTICLES COMPRISING THE SAME MASCO CORPORATION (US) 2009-07-16 WO disclosed
EP-2077301-A2 Scrub and stain-resistant coating Rohm and Haas Company (US) 2009-07-08 EP disclosed
EP-1845142-A1 Dirt pickup resistant coating binder having high adhesion to substrates Rohm and Haas Company (US) 2007-10-17 EP disclosed
EP-1798258-A1 Polymer composition Rohm and Haas Company (US) 2007-06-20 EP disclosed