Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615361 | 0.85 | MCL1 (0.59) | MCL1ALDH1A1KDM4ECYP3A4ACACB | |
| SCHEMBL9442189 | 0.83 | MCL1 (0.56) | MCL1ALDH1A1KDM4ECYP3A4ACACB | |
| SCHEMBL10428328 | 0.80 | MCL1 (0.60) | MCL1ALDH1A1KDM4ECYP3A4KMT2A | |
| SCHEMBL6616332 | 0.79 | MCL1 (0.52) | MCL1ALDH1A1KDM4ECYP3A4ACACB | |
| SCHEMBL8072203 | 0.78 | MCL1 (0.50) | MCL1ALDH1A1KDM4ECYP3A4KMT2A | |
| SCHEMBL24988613 | 0.76 | MCL1 (0.48) | MCL1ALDH1A1KDM4ECYP3A4KMT2A | |
| SCHEMBL8077349 | 0.75 | MCL1 (0.52) | MCL1ALDH1A1KDM4ECYP3A4ACACB | |
| SCHEMBL15903262 | 0.75 | ALDH1A1 (0.54) | ALDH1A1HPGDCYP2C19CYP2D6 | |
| SCHEMBL5154225 | 0.75 | — | — | |
| SCHEMBL8536470 | 0.74 | MCL1 (0.53) | MCL1ALDH1A1KDM4ECYP3A4ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785627-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8501890-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-08-06 | — | — | US | disclosed |
| US-8360576-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-01-29 | — | — | US | disclosed |
| US-8360576-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-01-29 | — | — | US | disclosed |
| EP-1815274-B1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | ABBOTT MEDICAL OPTICS INC (US) | 2011-09-21 | — | — | EP | disclosed |
| US-7989572-B2 | Polyvinyl ultraviolet light absorbers for personal care | EASTMAN CHEMICAL COMPANY (US) | 2011-08-02 | — | — | US | disclosed |
| WO-2009091506-A2 | POLYVINYL ULTRAVIOLET LIGHT ABSORBERS FOR PERSONAL CARE | EASTMAN CHEMICAL COMPANY (US) | 2009-07-23 | — | — | WO | disclosed |
| US-20090185988-A1 | POLYVINYL ULTRAVIOLET LIGHT ABSORBERS FOR PERSONAL CARE | EASTMAN CHEMICAL COMPANY (US) | 2009-07-23 | — | — | US | disclosed |
| US-20090076235-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | Johnson & Johnson Surgical Vision, Inc. | 2009-03-19 | — | — | US | disclosed |
| US-20090076235-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | Johnson & Johnson Surgical Vision, Inc. | 2009-03-19 | — | — | US | disclosed |
| US-4948879-A | Monoazo compounds containing a fiber-reactive group and an oxazolopyridone or oxazinopyridone coupling component | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090185988-A1 | POLYVINYL ULTRAVIOLET LIGHT ABSORBERS FOR PERSONAL CARE | MMS19, XPA, CUTA | MCL1 1796/4885ALDH1A1 1754/4885KDM4E 3348/4885 |
| US-20090076235-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | AAAS, IK, CYBA | MCL1 4158/4885ALDH1A1 868/4885KDM4E 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.