SCHEMBL615361

SCHEMBL615361

CC(C)CNC(=O)CC#N

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 4/20 0.59
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48
MMP1 P03956 1/20 0.42
MMP8 P22894 1/20 0.42
HPGD P15428 4/20 0.42
RECQL P46063 1/20 0.40
USP2 O75604 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP3A4 P08684 1/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPT P10636 1/20 0.36
EPHX1 P07099 1/20 0.36
ACACB O00763 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10428283 0.85 MCL1 (0.57) MCL1CYP2D6CYP2C19HPGDALDH1A1
SCHEMBL6027601 0.84 ALDH1A1 (0.53) MCL1CYP2D6CYP2C19MMP1MMP8
SCHEMBL6616332 0.80 MCL1 (0.52) MCL1CYP2C19ALDH1A1KDM4ECYP3A4
SCHEMBL26073789 0.80 CYP2D6 (0.50) CYP2D6CYP2C19MMP1MMP8HPGD
SCHEMBL9442189 0.80 MCL1 (0.56) MCL1ALDH1A1KDM4ECYP3A4GAA
SCHEMBL6322096 0.79 MCL1 (0.62) MCL1CYP2C19HPGDALDH1A1LMNA
SCHEMBL16674188 0.78 CYP2D6 (0.48) CYP2D6CYP2C19MMP1MMP8HPGD
SCHEMBL8077349 0.77 MCL1 (0.52) MCL1ALDH1A1KDM4ECYP3A4GAA
SCHEMBL5154225 0.77
SCHEMBL8536470 0.76 MCL1 (0.53) MCL1ALDH1A1KDM4ECYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4283520-A USING A CYANOACETYL CURING AGENT AND A PHENYLUREA ACCELERATOR CIBA-GEIGY CORPORATION (US) 1981-08-11 US claimed
US-4202920-A Cyanoacetic acid derivatives as epoxy resin curing agents CIBA-GEIGY CORPORATION (US) 1980-05-13 US claimed
US-11976075-B2 Inhibitors of the MYST family of lysine acetyl transferases Isosterix, Inc. 2024-05-07 US disclosed
CN-115195104-B Dual precursor resin system for additive manufacturing with dual cure resins 卡本有限公司 2023-12-05 CN disclosed
US-11834574-B2 Dual cure additive manufacturing resins for production of flame retardant objects CARBON, INC. (US) 2023-12-05 US disclosed
US-11833744-B2 Dual precursor resin systems for additive manufacturing with dual cure resins CARBON, INC. (US) 2023-12-05 US disclosed
US-11814472-B2 Epoxy dual cure resins for additive manufacturing CARBON, INC. (US) 2023-11-14 US disclosed
US-20230303580-A1 INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES Isosterix, Inc. 2023-09-28 US disclosed
US-20230303580-A1 INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES Isosterix, Inc. 2023-09-28 US disclosed
US-20230143277-A1 DUAL CURE STEREOLITHOGRAPHY RESINS CONTAINING DIELS-ALDER ADDUCTS CARBON INC (US) 2023-05-11 US disclosed
US-11629202-B2 Dual cure stereolithography resins containing thermoplastic particles CARBON, INC. (US) 2023-04-18 US disclosed
US-6313257-B1 Poly (mercaptopropylaryl) curatives LORD CORPORATION 2001-11-06 US disclosed
WO-2001000698-A2 POLY(MERCAPTOPROPYLARYL) CURATIVES LORD CORPORATION (US) 2001-01-04 WO disclosed
US-5214098-A Dicyandiamide, impregnation of fiber composites, prepregs CIBA-GEIGY CORPORATION (US) 1993-05-25 US disclosed
US-4562241-A CURING AGENTS FOR POLYEPOXIDES CIBA-GEIGY CORPORATION (US) 1985-12-31 US disclosed
US-4283520-A USING A CYANOACETYL CURING AGENT AND A PHENYLUREA ACCELERATOR CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed
US-4202920-A Cyanoacetic acid derivatives as epoxy resin curing agents CIBA-GEIGY CORPORATION (US) 1980-05-13 US disclosed
US-4108630-A 1-Alkylpyrid-2-ones ROHM AND HAAS COMPANY (US) 1978-08-22 US disclosed
US-4038065-A 1-ALKYLPYRID-2-ONE ROHM AND HAAS COMPANY (US) 1977-07-26 US disclosed
US-3985763-A DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303580-A1 INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES KAT6A, KAT6B, KAT2A MCL1 638/4885CYP2D6 3215/4885CYP2C19 4583/4885
US-11976075-B2 Inhibitors of the MYST family of lysine acetyl transferases KAT6A, KAT6B, KAT2A MCL1 638/4885CYP2D6 3215/4885CYP2C19 4583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.