Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908259 | 0.85 | — | — | |
| SCHEMBL14175445 | 0.85 | — | — | |
| SCHEMBL8428366 | 0.84 | TLR4 (0.36) | TLR4 | |
| SCHEMBL9234017 | 0.80 | TRIM24 (0.41) | — | |
| SCHEMBL8220510 | 0.80 | — | — | |
| SCHEMBL14175453 | 0.78 | — | — | |
| SCHEMBL8448821 | 0.77 | TLR4 (0.36) | TLR4 | |
| SCHEMBL6659962 | 0.77 | TLR4 (0.36) | TLR4 | |
| SCHEMBL510704 | 0.77 | TRIM24 (0.44) | — | |
| SCHEMBL1666553 | 0.74 | TLR4 (0.51) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385067-B2 | Process for the preparation of compounds having a CF2O bridge | MERCK PATENT GMBH (DE) | 2008-06-10 | — | — | US | disclosed |
| US-7385067-B2 | Process for the preparation of compounds having a CF2O bridge | MERCK PATENT GMBH (DE) | 2008-06-10 | — | — | US | disclosed |