Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448821 | 1.00 | TLR4 (0.36) | TLR4HTT | |
| SCHEMBL28323969 | 0.90 | TLR4 (0.40) | TLR4 | |
| SCHEMBL87369 | 0.85 | — | — | |
| SCHEMBL6453332 | 0.85 | TLR4 (0.38) | TLR4 | |
| SCHEMBL6453335 | 0.85 | TLR4 (0.38) | TLR4 | |
| SCHEMBL6453339 | 0.85 | TLR4 (0.38) | TLR4 | |
| SCHEMBL8215701 | 0.83 | TLR4 (0.51) | TLR4 | |
| SCHEMBL1666553 | 0.83 | TLR4 (0.51) | TLR4 | |
| SCHEMBL1666552 | 0.83 | TLR4 (0.51) | TLR4 | |
| SCHEMBL22443230 | 0.82 | TLR4 (0.35) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |
| US-9839664-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-12-12 | — | — | US | disclosed |
| US-20170216392-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2017-08-03 | — | — | US | disclosed |
| US-9474755-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SARL (CH) | 2016-10-25 | — | — | US | disclosed |
| US-20160038487-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-02-11 | — | — | US | disclosed |
| CN-103725292-B | Negative dielectric anisotropy liquid crystal compound and liquid crystal composition comprising same | DAXIN MATERIALS CORP. (CN) | 2016-01-20 | — | — | CN | disclosed |
| US-9133396-B2 | Liquid crystal compound having negative dielectric anisotropy, and liquid crystal composition | DAXIN MATERIALS CORP. (TW) | 2015-09-15 | — | — | US | disclosed |
| US-9133396-B2 | Liquid crystal compound having negative dielectric anisotropy, and liquid crystal composition | DAXIN MATERIALS CORP. (TW) | 2015-09-15 | — | — | US | disclosed |
| US-9133396-B2 | Liquid crystal compound having negative dielectric anisotropy, and liquid crystal composition | DAXIN MATERIALS CORP. (TW) | 2015-09-15 | — | — | US | disclosed |
| CN-103725292-A | Negative dielectric anisotropy liquid crystal compound and liquid crystal composition comprising same | DAXIN MATERIALS CORP | 2014-04-16 | — | — | CN | disclosed |
| EP-1010702-A2 | Process for preparing ortho-substituted aryl metal compounds and their conversion with electrophiles | MERCK PATENT GmbH (DE) | 2000-06-21 | — | — | EP | disclosed |
| US-5976408-A | Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0820983-A1 | ACRYLONITRILE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-4617141-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1986-10-14 | — | — | US | disclosed |
| EP-0084974-B1 | CARBOCYCLIC COMPOUNDS WITH LIQUID-CRYSTAL PROPERTIES | Chisso Corporation (JP) | 1986-04-02 | — | — | EP | disclosed |
| EP-0096850-B1 | TRANS-4-ALKYLOXYMETHYL-1-(4'-SUBSTITUTED BIPHENYLYL-4)CYCLOHEXANES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | Chisso Corporation (JP) | 1985-09-25 | — | — | EP | disclosed |
| US-4522741-A | Trans-4-alkyloxymethyl-1-(4'-substituted biphenylyl-4)cyclohexanes | CHISSO CORPORATION (JP) | 1985-06-11 | — | — | US | disclosed |
| US-4477369-A | New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same | CHISSO CORPORATION (JP) | 1984-10-16 | — | — | US | disclosed |
| EP-0096850-A1 | Trans-4-alkyloxymethyl-1-(4'-substituted biphenylyl-4)cyclohexanes and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1983-12-28 | — | — | EP | disclosed |
| EP-0084974-A1 | Carbocyclic compounds with liquid-crystal properties | Chisso Corporation (JP) | 1983-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216392-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | TLR4 1273/4885HTT 1006/4885 |
| US-20160038487-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | TLR4 1273/4885HTT 1006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.