SCHEMBL8428366

SCHEMBL8428366

O=C1CCC(C2CCC(CCF)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14175477 0.84 TLR4 (0.30) TLR4
SCHEMBL8209246 0.83
SCHEMBL1666552 0.81 TLR4 (0.51) TLR4
SCHEMBL1666553 0.81 TLR4 (0.51) TLR4
SCHEMBL8215701 0.81 TLR4 (0.51) TLR4
SCHEMBL9234017 0.78 TRIM24 (0.41)
SCHEMBL28670982 0.78 TRIM24 (0.41)
SCHEMBL7782150 0.78 CYP1A2 (0.47) TLR4
SCHEMBL6734843 0.78 CYP1A2 (0.47) TLR4
SCHEMBL6752745 0.78 CYP1A2 (0.47) TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718264-B1 A liquid crystalline compound containing fluorine atom substituted alkyl group(s) and a liquid crystal composition CHISSO CORP (JP) 1999-11-17 EP disclosed
US-5702641-A ELECTRICAL AND CHEMICAL STABILITY CHISSO CORPORATION (JP) 1997-12-30 US disclosed
EP-0718264-A1 A liquid crystalline compound containing fluorine atom substituted alkyl group(s) and a liquid crystal composition Chisso Corporation (JP) 1996-06-26 EP disclosed