SCHEMBL14176743

SCHEMBL14176743

CC(C)NC(=O)c1ccccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 4/20 0.59
▸ MEN1 O00255 3/20 0.59
▸ KMT2A Q03164 3/20 0.59
▸ POLB P06746 2/20 0.59
▸ ATM Q13315 2/20 0.59
▸ PLEC Q15149 1/20 0.59
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ ALPL P05186 1/20 0.51
▸ ALPI P09923 1/20 0.51
▸ ALPG P10696 1/20 0.51
▸ GJA1 P17302 1/20 0.49
▸ GJB2 P29033 1/20 0.49
▸ CA9 Q16790 9/20 0.48
▸ CA1 P00915 7/20 0.48
▸ CA2 P00918 7/20 0.48
▸ CA12 O43570 2/20 0.48
▸ DNASE1L3 Q13609 1/20 0.48
▸ PRMT1 Q99873 1/20 0.48
▸ ABCB1 P08183 1/20 0.47
▸ CDC25A P30304 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14193707 0.89 USP2 (0.63) USP2MEN1KMT2APOLBATM
SCHEMBL12295575 0.86 USP2 (0.63) USP2MEN1KMT2APOLBATM
SCHEMBL20910261 0.86 USP2 (0.63) USP2MEN1KMT2APOLBATM
SCHEMBL20053383 0.85 USP2 (0.66) USP2MEN1KMT2APOLBATM
SCHEMBL16692409 0.85 USP2 (0.67) USP2MEN1KMT2APOLBATM
SCHEMBL29591827 0.84 USP2 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL29781098 0.84 USP2 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL107875 0.84 USP2 (0.76) USP2MEN1KMT2APOLBATM
SCHEMBL23467779 0.84 USP2 (0.59) USP2MEN1KMT2APOLBATM
SCHEMBL16579859 0.83 USP2 (0.56) USP2MEN1KMT2APOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080138817-A1 Novel Functional Peptide Nucleic Acid Monomer and Process for Producing the Same CREDIA JAPAN CO., LTD. (JP) 2008-06-12 — — US disclosed
US-7282575-B2 Functional peptide nucleic acid monomer and process for producing the same CREDIA JAPAN CO., LTD. (JP) 2007-10-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138817-A1 Novel Functional Peptide Nucleic Acid Monomer and Process for Producing the Same NSUN3, RNGTT, NSUN2 USP2 2830/4885MEN1 3066/4885KMT2A 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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