SCHEMBL20053383

SCHEMBL20053383

CC(C)NC(=O)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.66
L3MBTL1 Q9Y468 1/20 0.66
CA9 Q16790 8/20 0.61
ALB P02768 2/20 0.57
MEN1 O00255 2/20 0.56
POLB P06746 2/20 0.56
KMT2A Q03164 2/20 0.56
ALPL P05186 1/20 0.56
ALPI P09923 1/20 0.56
ALPG P10696 1/20 0.56
CA1 P00915 6/20 0.54
CA2 P00918 6/20 0.54
CA12 O43570 2/20 0.54
ESR1 P03372 1/20 0.54
FOLH1 Q04609 3/20 0.53
ATM Q13315 1/20 0.53
PLEC Q15149 1/20 0.53
DNASE1L3 Q13609 1/20 0.52
PRMT1 Q99873 1/20 0.52
CA14 Q9ULX7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13497987 0.93 USP2 (0.59) USP2L3MBTL1CA9ALBMEN1
SCHEMBL10138306 0.89 USP2 (0.69) USP2L3MBTL1CA9ALBMEN1
SCHEMBL19543669 0.87 USP2 (0.69) USP2L3MBTL1CA9ALBMEN1
SCHEMBL13656547 0.87 USP2 (0.72) USP2L3MBTL1CA9ALBMEN1
SCHEMBL15087770 0.87 USP2 (0.61) USP2L3MBTL1CA9ALBMEN1
SCHEMBL1437042 0.87 USP2 (0.78) USP2L3MBTL1CA9ALBMEN1
SCHEMBL10123977 0.86 USP2 (0.66) USP2L3MBTL1CA9ALBMEN1
SCHEMBL10153957 0.86 USP2 (0.66) USP2L3MBTL1CA9ALBMEN1
SCHEMBL20143683 0.86 USP2 (0.60) USP2L3MBTL1CA9ALBMEN1
SCHEMBL173061 0.86 USP2 (0.73) USP2L3MBTL1CA9ALBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9944752-B2 Block copolymers for stable micelles INTEZYNE TECHNOLOGIES, INC. (US) 2018-04-17 US disclosed