SCHEMBL16690689

SCHEMBL16690689

CC(C)SOSc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MGLL Q99685 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC6A4 P31645 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
MTNR1A P48039 3/20 0.31
MTNR1B P49286 3/20 0.31
PTPN1 P18031 1/20 0.31
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
KCNH2 Q12809 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141775 0.77 HPGD (0.50) MAOAMAOBMAPTHPGDSMN1; SMN2
SCHEMBL21035917 0.71 MAOA (0.40) MAOAMAOBMAPTHPGDSMN1; SMN2
SCHEMBL11143252 0.70 HPGD (0.38) MAPTHPGDSMN1; SMN2MGLLHSD17B10
SCHEMBL1453001 0.67 SMN1; SMN2 (0.45) MAOAMAOBMAPTHPGDSMN1; SMN2
SCHEMBL5695276 0.67
SCHEMBL343269 0.67 SMN1; SMN2 (0.45) MAOAMAOBMAPTHPGDSMN1; SMN2
SCHEMBL3227622 0.67 CA4 (0.42) MAOAHPGDALDH1A1MTNR1AMTNR1B
SCHEMBL8763072 0.67 CA4 (0.54) HPGDSMN1; SMN2ALDH1A1TDP1
Fluoride SCHEMBL1336886 0.65 MAOA (0.48) MAOAMAOBMAPTHPGDSMN1; SMN2
SCHEMBL40461 0.65 MAPT (0.43) MAOAMAOBMAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039010-B1 ARYL NAPHTHYL METHANONE OXIME(S) AND PROCESS FOR PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2017-10-11 EP disclosed
EP-2934535-B1 SUBSTITUTED PYRROLOPYRIMIDINES AS HDM2 INHIBITORS MERCK SHARP & DOHME (US) 2017-07-19 EP disclosed
US-20170184973-A1 ORGANIC TREATMENT LIQUID FOR PATTERNING RESIST FILM, METHOD OF PRODUCING ORGANIC TREATMENT LIQUID FOR PATTERNING RESIST FILM, STORAGE CONTAINER OF ORGANIC TREATMENT LIQUID FOR PATTERNING RESIST FILM, PATTERN FORMING METHOD USING THE SAME, AND METHOD OF PRODUCING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2017-06-29 US disclosed
EP-1801651-B1 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORP (JP) 2017-04-19 EP disclosed
EP-2869367-A1 NEGATIVE ACTIVE MATERIAL FOR SECONDARY BATTERY, PROCESS FOR PRODUCING SAME, AND NEGATIVE ELECTRODE AND LITHIUM-ION BATTERY BOTH OBTAINED USING SAME JNC Corporation (JP) 2015-05-06 EP disclosed
US-20140066290-A1 CATHODE CATALYST FOR AIR SECONDARY BATTERY AND AIR SECONDARY BATTERY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-06 US disclosed
US-20130123514-A1 CARBOCATALYSTS FOR CHEMICAL TRANSFORMATIONS GRAPHEA, INC. (US) 2013-05-16 US disclosed
US-20120322728-A1 PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF DIABETES MELLITUS AND OTHER METABOLIC DISEASES METABOLIC SOLUTIONS DEVELOPMENT COMPANY, LLC (US) 2012-12-20 US disclosed
US-8258251-B2 Highly porous ceramic oxide aerogels having improved flexibility THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2012-09-04 US disclosed
US-20120082835-A1 STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2012-04-05 US disclosed
US-7858968-B2 Field effect transistor and method of fabricating the same PANASONIC CORPORATION (JP) 2010-12-28 US disclosed
US-20100283174-A1 Fabrication of polymer grafted carbon nanotubes/polypropylene composite bipolar plates for fuel cell YUAN ZE UNIVERSITY (TW) 2010-11-11 US disclosed
US-20100234503-A1 POLYMER COMPOSITES MECHANICALLY REINFORCED WITH ALKYL AND UREA FUNCTIONALIZED NANOTUBES WILLIAM MARSH RICE UNIVERSITY 2010-09-16 US disclosed
US-20100224867-A1 ELECTRONIC DEVICES COMPRISING STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100228025-A1 STRUCTURED ORGANIC FILMS HAVING AN ADDED FUNCTIONALITY XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100119822-A1 CARBON NANOTUBE COPOLYMERS AND COMPOSITIONS AND METHODS OF USING THE SAME SPIRIT AEROSYSTEMS, INC. (US) 2010-05-13 US disclosed
US-7399819-B2 Silicon compound CHISSO CORPORATION (JP) 2008-07-15 US disclosed
US-20080023884-A1 Method for preparing poly(dicyclopentadiene) DOW GLOBAL TECHNOLOGIES INC. 2008-01-31 US disclosed
US-20070131915-A1 Stable dispersions of polymer-coated graphitic nanoplatelets NORTHWESTERN UNIVERSITY 2007-06-14 US disclosed
US-20070108480-A1 Field effect transistor and method of fabricating the same PANASONIC CORPORATION (JP) 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100224867-A1 ELECTRONIC DEVICES COMPRISING STRUCTURED ORGANIC FILMS EPCAM, EPHA6, EED MAOA 100/4885MAOB 255/4885MAPT 787/4885
US-20100228025-A1 STRUCTURED ORGANIC FILMS HAVING AN ADDED FUNCTIONALITY VIM, PUF60, EPCAM MAOA 7/4885MAOB 76/4885MAPT 376/4885
US-20130123514-A1 CARBOCATALYSTS FOR CHEMICAL TRANSFORMATIONS TDO2, VIM, COMT MAOA 568/4885MAOB 1014/4885MAPT 2473/4885
US-20170184973-A1 ORGANIC TREATMENT LIQUID FOR PATTERNING RESIST FILM, METHOD OF PRODUCING ORGANIC TREATMENT LIQUID FOR PATTERNING RESIST FILM, STORAGE CONTAINER OF ORGANIC TREATMENT LIQUID FOR PATTERNING RESIST FILM, PATTERN FORMING METHOD USING THE SAME, AND METHOD OF PRODUCING ELECTRONIC DEVICE MYB, NCL, SMYD2 MAOA 218/4885MAOB 633/4885MAPT 52/4885
US-20120322728-A1 PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF DIABETES MELLITUS AND OTHER METABOLIC DISEASES GLP1R, PPARD, PPARA MAOA 3906/4885MAOB 4252/4885MAPT 4608/4885
US-20120082835-A1 STRUCTURED ORGANIC FILMS VIM, PUF60, EPCAM MAOA 53/4885MAOB 197/4885MAPT 270/4885
US-20100234503-A1 POLYMER COMPOSITES MECHANICALLY REINFORCED WITH ALKYL AND UREA FUNCTIONALIZED NANOTUBES RNMT, CAPG, POT1 MAOA 2212/4885MAOB 3351/4885MAPT 932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.