Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14178706 | 0.92 | MEN1 (0.40) | MEN1KMT2AHIF1AEPAS1MAPT | |
| SCHEMBL14178710 | 0.85 | MEN1 (0.40) | MEN1KMT2AHIF1AEPAS1MAPT | |
| SCHEMBL14178676 | 0.84 | HIF1A (0.51) | MEN1KMT2AHIF1AEPAS1NPC1 | |
| SCHEMBL14178675 | 0.84 | HIF1A (0.51) | MEN1KMT2AHIF1AEPAS1NPC1 | |
| SCHEMBL14178686 | 0.83 | MEN1 (0.41) | MEN1KMT2AHIF1AEPAS1MAPT | |
| SCHEMBL14178692 | 0.79 | HIF1A (0.50) | MEN1KMT2AHIF1AEPAS1MAPT | |
| SCHEMBL14178711 | 0.75 | CRHR1 (0.38) | ACP1MEN1KMT2AHIF1AEPAS1 | |
| SCHEMBL14178672 | 0.74 | HIF1A (0.47) | MEN1KMT2AHIF1AEPAS1LMNA | |
| SCHEMBL14178681 | 0.74 | HIF1A (0.49) | MEN1KMT2AHIF1AEPAS1NPC1 | |
| SCHEMBL4799196 | 0.74 | PTGS1 (0.38) | HIF1AEPAS1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |