Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14178710 | 0.91 | MEN1 (0.40) | MEN1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL14178706 | 0.91 | MEN1 (0.40) | MEN1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL14178692 | 0.88 | HIF1A (0.50) | MEN1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL14178685 | 0.86 | LMNA (0.34) | MEN1MAPTCRHBPKMT2ACRHR2 | |
| SCHEMBL14178696 | 0.83 | NCF1 (0.39) | MEN1MAPTKMT2AHIF1AEPAS1 | |
| SCHEMBL14180218 | 0.81 | HIF1A (0.40) | MEN1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL14178674 | 0.81 | HIF1A (0.48) | MEN1MAPTKMT2AHIF1AEPAS1 | |
| SCHEMBL14178711 | 0.77 | CRHR1 (0.38) | MEN1MAPTKMT2AHIF1AEPAS1 | |
| SCHEMBL2557901 | 0.77 | HIF1A (0.52) | MEN1CYP1A2CYP3A4MAPTCYP2C9 | |
| SCHEMBL14178684 | 0.73 | HIF1A (0.43) | MAPTHIF1AEPAS1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |
| US-7368575-B2 | 6-alkylamino-2,2′-disubstituted-7,8-disubstituted-2H-1-benzopyran derivatives as 5-lipoxygenase inhibitor | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-06 | — | — | US | disclosed |