Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805929 | 0.84 | CNR1 (0.47) | CNR1SMN1; SMN2MAPK1GAARAB9A | |
| SCHEMBL14180756 | 0.83 | CNR1 (0.46) | CNR1SMN1; SMN2RAB9ANPSR1LMNA | |
| SCHEMBL14180961 | 0.82 | CNR1 (0.48) | CNR1SMN1; SMN2RAB9ANPSR1LMNA | |
| SCHEMBL14180963 | 0.82 | CNR1 (0.48) | CNR1SMN1; SMN2RAB9ANPSR1LMNA | |
| SCHEMBL14180939 | 0.80 | CNR1 (0.47) | CNR1SMN1; SMN2RAB9ANPSR1LMNA | |
| SCHEMBL14180951 | 0.79 | CNR1 (0.48) | CNR1SMN1; SMN2RAB9ANPSR1LMNA | |
| SCHEMBL14180949 | 0.79 | CNR1 (0.47) | CNR1SMN1; SMN2MAPK1RAB9AHTT | |
| SCHEMBL14180952 | 0.78 | CNR1 (0.47) | CNR1SMN1; SMN2MAPK1LMNAKDM4E | |
| SCHEMBL4803516 | 0.77 | CNR1 (0.49) | CNR1SMN1; SMN2RAB9AKDM4EMAPT | |
| SCHEMBL14180958 | 0.77 | CNR1 (0.46) | CNR1SMN1; SMN2MAPK1HTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |