SCHEMBL14181740

SCHEMBL14181740

Cc1ccc(N(c2ccc(C)cc2)c2c3ccccc3c(-c3ccc(-c4cc(C)cc(-c5ccc(-c6c7ccccc7c(N(c7ccc(C)cc7)c7ccc(C)cc7)c7ccccc67)cc5)c4)cc3)c3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.38
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
GSK3B P49841 1/20 0.31
ADK P55263 1/20 0.31
RAB9A P51151 3/20 0.31
MAOB P27338 2/20 0.31
NPC1 O15118 2/20 0.31
TNKS O95271 1/20 0.31
PARP1 P09874 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
PARP2 Q9UGN5 1/20 0.31
HPRT1 P00492 1/20 0.31
RCE1 Q9Y256 1/20 0.31
CTSV O60911 1/20 0.31
CTSL P07711 1/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1753732 0.94 ACHE (0.35) ACHEMEN1KMT2ARAB9AMAOB
SCHEMBL14577020 0.92 ACHE (0.41) ACHEMEN1KMT2AGSK3BADK
SCHEMBL13222601 0.91 ACHE (0.37) ACHEMEN1KMT2ARAB9AMAOB
SCHEMBL13222621 0.91 ACHE (0.44) ACHEMEN1KMT2AGSK3BADK
SCHEMBL14181747 0.90 ALOX5 (0.39) ACHEMEN1KMT2ARAB9ANPC1
SCHEMBL14181736 0.89 ACHE (0.42) ACHEMEN1KMT2AGSK3BADK
SCHEMBL12721991 0.88 ACHE (0.43) ACHEMEN1KMT2ARAB9ANPC1
SCHEMBL1753829 0.87 ACHE (0.33) ACHEALDH1A1NPSR1L3MBTL1KDM4E
SCHEMBL10128619 0.87 ACHE (0.41) ACHEGSK3BADKRAB9ANPC1
SCHEMBL14181734 0.87 ACHE (0.38) ACHEHPGDALDH1A1SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7375250-B2 Aminoanthryl derivative substitution compound and organic electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2008-05-20 US disclosed