SCHEMBL14181758

SCHEMBL14181758

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3c4ccccc4c(-c4cc(-c5c6ccccc6c(-c6ccc(N(c7ccc(C)cc7)c7ccc(C)cc7)cc6)c6ccccc56)cc(-c5c6ccccc6c(-c6ccc(N(c7ccc(C)cc7)c7ccc(C)cc7)cc6)c6ccccc56)c4)c4ccccc34)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.45
ALDH1A1 P00352 4/20 0.37
TSHR P16473 1/20 0.37
MAOB P27338 2/20 0.37
TNKS O95271 1/20 0.37
PARP1 P09874 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
PARP2 Q9UGN5 1/20 0.37
CTSV O60911 1/20 0.37
CTSL P07711 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
GSK3B P49841 1/20 0.36
ADK P55263 1/20 0.36
CYP2C19 P33261 1/20 0.36
PTGS2 P35354 2/20 0.36
PDE9A O76083 1/20 0.36
PDE1C Q14123 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
MEN1 O00255 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14181736 0.96 ACHE (0.42) ACHEALDH1A1TSHRMAOBTNKS
SCHEMBL1262728 0.96 ACHE (0.47) ACHEALDH1A1TSHRGSK3BADK
SCHEMBL14577020 0.93 ACHE (0.41) ACHEALDH1A1TSHRMAOBTNKS
SCHEMBL11954097 0.92 ACHE (0.45) ACHEALDH1A1TSHRGSK3BADK
SCHEMBL10063931 0.92 ACHE (0.45) ACHEALDH1A1TSHRGSK3BADK
SCHEMBL12619868 0.92 ACHE (0.45) ACHEALDH1A1TSHRGSK3BADK
SCHEMBL13222607 0.92 ALOX5 (0.44) ACHEALDH1A1TSHRHPGDRAB9A
SCHEMBL10064005 0.91 ACHE (0.47) ACHEALDH1A1TSHRHPGDRAB9A
SCHEMBL10063974 0.91 ACHE (0.47) ACHEALDH1A1TSHRHPGDRAB9A
SCHEMBL14160409 0.91 ACHE (0.47) ACHEALDH1A1TSHRHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7375250-B2 Aminoanthryl derivative substitution compound and organic electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2008-05-20 US disclosed
US-7375250-B2 Aminoanthryl derivative substitution compound and organic electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2008-05-20 US disclosed
US-7309533-B2 Substituted anthryl derivative and electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2007-12-18 US disclosed
US-7309533-B2 Substituted anthryl derivative and electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2007-12-18 US disclosed
US-7173131-B2 Anthryl derivative group substituted compound, and organic luminescent device making use of same CANON KABUSHIKI KAISHA (JP) 2007-02-06 US disclosed