SCHEMBL14181763

SCHEMBL14181763

Cc1ccc(N(c2ccc(C)cc2)c2c3ccccc3c(-c3cc(-c4c5ccccc5c(C)c5ccccc45)cc(-c4c5ccccc5c(N(c5ccc(C)cc5)c5ccc(C)cc5)c5ccccc45)c3)c3ccccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.34
CYP2C19 P33261 1/20 0.33
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAOB P27338 2/20 0.30
HPGD P15428 2/20 0.30
RAB9A P51151 2/20 0.30
TNKS O95271 1/20 0.30
PARP1 P09874 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
PARP2 Q9UGN5 1/20 0.30
CTSV O60911 1/20 0.30
CTSL P07711 1/20 0.30
HSD17B10 Q99714 2/20 0.30
KDM4E B2RXH2 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13222601 0.95 ACHE (0.37) ACHECYP2C19TSHRALDH1A1MAOB
SCHEMBL1753732 0.92 ACHE (0.35) ACHECYP2C19TSHRALDH1A1MAOB
SCHEMBL14577020 0.90 ACHE (0.41) ACHECYP2C19TSHRALDH1A1MAOB
SCHEMBL13222563 0.90 ACHE (0.37) ACHECYP2C19TSHRALDH1A1MAOB
SCHEMBL16982401 0.89 TSHR (0.39) ACHECYP2C19TSHRALDH1A1HPGD
SCHEMBL13222621 0.88 ACHE (0.44) ACHECYP2C19TSHRALDH1A1NPSR1
SCHEMBL14212215 0.87 ACHE (0.33) ACHECYP2C19TSHRALDH1A1HPGD
SCHEMBL14195788 0.87 ACHE (0.33) ACHECYP2C19TSHRALDH1A1
SCHEMBL13222604 0.87 ALOX5 (0.39) ACHEALDH1A1HPGDRAB9AHSD17B10
SCHEMBL14195789 0.87 ALOX5 (0.39) ACHEALDH1A1HPGDRAB9AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7375250-B2 Aminoanthryl derivative substitution compound and organic electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2008-05-20 US disclosed
US-7375250-B2 Aminoanthryl derivative substitution compound and organic electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2008-05-20 US disclosed
US-7309533-B2 Substituted anthryl derivative and electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2007-12-18 US disclosed
US-7309533-B2 Substituted anthryl derivative and electroluminescence device using the same CANON KABUSHIKI KAISHA (JP) 2007-12-18 US disclosed
US-7173131-B2 Anthryl derivative group substituted compound, and organic luminescent device making use of same CANON KABUSHIKI KAISHA (JP) 2007-02-06 US disclosed
US-7173131-B2 Anthryl derivative group substituted compound, and organic luminescent device making use of same CANON KABUSHIKI KAISHA (JP) 2007-02-06 US disclosed